Results 81 to 90 of about 2,559,715 (278)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Intergenerational family ties and the diffusion of cohabitation in Italy [PDF]

open access: yes
Cohabitation has been spreading in the population during the last thirty years, and this is one of the most striking aspects of wider social changes that have taken place throughout the industrialized world.
Alessandro Rosina, Paola Di Giulio
core  

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Is There a Place for Islam in the West? Adjudicating the Muslim Headscarf in Europe and the United States [PDF]

open access: yes, 2017
The short essay describes the two judgments (Achbita and Bougnauoi) of the CJEU that addressed the issue of the Islamic veil in the workplace. It explores its newness and implications, in the light of the American experience as well as of the European ...
Pin, Andrea
core   +1 more source

Pan-European Chikungunya surveillance: Designing risk stratified surveillance zones [PDF]

open access: yes, 2009
This article has been made available through the Brunel Open Access Publishing Fund - Copyright @ 2009 Tilston et alThe first documented transmission of Chikungunya within Europe took place in Italy during the summer of 2007.
Skelly, C, Tilston, N, Weinstein, P
core   +4 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

The Estimation of Place-to-Place Migration Flows Using an Alternative Log-Linear Parameter Coding Scheme

open access: yes, 2004
The log-linear model, with an alternative parameter coding scheme, is used in this paper to obtain estimates of place-to-place migration flows in situations where the data are inadequate or missing. The alternative parameter coding scheme is particularly
Raymer, James
core  

Innovation diplomacy caught between the two opposing logics of cooperation and competition: Case study on EU-China S&T cooperation in the field of solar PV. EL-CSID Working Paper Issue 2018/15 • April 2018 [PDF]

open access: yes, 2018
The purpose of this study is to test this question on the basis of a highly interesting illustrative case. It concerns the domain of the solar photovoltaics (solar PV) and the competition between the EU and China in this field.
Gehrt, Daniel
core  

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

European Citizens’ Panel on the future of Europe Bertelsmann Stiftung Evaluation Report [PDF]

open access: yes, 2018
New forms of democratic participation are gaining ground rapidly. Many EU Member States have reacted to their citizens’ increasing demands for participation.
Hierlemann, Dominik, Huesmann, Christian
core  

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