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Plasticity of the Hippocampal Place Cell Representation
Reviews in the Neurosciences, 2004The role of the hippocampus in the representation of 'place' has been attributed to the place cells, whose spatially localised firing suggests their participation in forming a cognitive map of the environment. That this map is necessary for spatial memory formation is indicated by the propensity of almost all navigational tasks to be disrupted by ...
Kathryn J, Jeffery, Robin, Hayman
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Overview of asthma; the place of the T cell
Current Opinion in Pharmacology, 2010Asthma is an inflammatory disease which is associated with activated T cells in the airway wall. The contribution of the T lymphocyte to inflammation in asthma has been extensively studied through descriptions of T cell subsets in the airway wall of asthmatic patients and from animal and cellular models.
Karim H, Shalaby, James G, Martin
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Science, 2003
STKE Vascular proliferative diseases, such as atherosclerosis and coronary restenosis, are characterized by dedifferentiation, abnormal proliferation, and migration of vascular smooth muscle cells, a pathophysiological reaction to injury that has been interpreted as a response to cytokines released by inflammatory cells.
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STKE Vascular proliferative diseases, such as atherosclerosis and coronary restenosis, are characterized by dedifferentiation, abnormal proliferation, and migration of vascular smooth muscle cells, a pathophysiological reaction to injury that has been interpreted as a response to cytokines released by inflammatory cells.
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On the placing of balls in cells
International Journal of Mathematical Education in Science and Technology, 1998In this paper we suggest that those who teach probability calculus and the foundations of mathematical statistics should give attention to the problem described.
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PLACE CELLS. Autoassociative dynamics in the generation of sequences of hippocampal place cells.
Science (New York, N.Y.), 2015Neuronal circuits produce self-sustaining sequences of activity patterns, but the precise mechanisms remain unknown. Here we provide evidence for autoassociative dynamics in sequence generation. During sharp-wave ripple (SWR) events, hippocampal neurons express sequenced reactivations, which we show are composed of discrete attractors.
Brad E, Pfeiffer, David J, Foster
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Stochastic model of the place cell discharge
1999The firing activity of place cells of the hippocampus reflects movements of an animal in its experimental area. This well known fact was recently reinvestigated (Fenton and Muller, 1998) and it was found that while the activity was highly reliable in space, it did not retain the same reliability in time. The number of spikes discharged during different
Petr Lánský, Jean Vaillant
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Noradrenergic regulation of hippocampal place cells
Hippocampus, 2001AbstractThe influence of noradrenergic input to the hippocampus was assessed by recording hippocampal place cells and by modulating the noradrenergic tone with a selective agonist and antagonist of the α2‐autoreceptors. The rats received intraperitoneal injection of 5 μg/kg of dexmedetomidine (DEX), an α2‐agonist, 0.2 mg/kg of atipamezole (ATI), an α2 ...
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Some thoughts on place cells and the hippocampus
Hippocampus, 1999This commentary addresses five issues related to the functional role of place cells and the hippocampus. 1. Is the cognitive map located in the hippocampus? Not exclusively. 2. Is the hippocampus required for path integration? Not exclusively. 3. Is the hippocampus involved in selecting the appropriate reference frame? Not exclusively. 4.
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Place cells, grid cells, and the brain's spatial representation system.
Annual Review of Neuroscience, 2008E. Moser, E. Kropff, M. Moser
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