Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Using structural equation modelling to examine the relationship between place identity, sense of community, and environmental attitude. [PDF]
Karaçor EK, Akçam E.
europepmc +1 more source
“God’s little acre” and “Belfast Chinatown”: Diversity and Ethnic Place Identity in Belfast [PDF]
For members of ethnic minorities in Northern Ireland, place making can mean negotiating challenges posed by tensions between the two majority communities of Catholic, nationalist, republican and Protestant, unionist, loyalist; tensions which are ...
Suzanna Chan
core
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Institutional Place Identity and Life Adaptation among Elderly People in Taiwan. [PDF]
Chuang NC, Kuo PC, Chiu YW.
europepmc +1 more source
Atlantic Exchange: Case Studies of Housing and Community Redevelopment in the United States and the United Kingdom [PDF]
Examines lessons learned from community redevelopment initiatives in Birmingham, England, and Chicago. Explores physical, managerial, and demographic changes and issues of place identity, community cohesion, and the communities' place in city ...
David Price +3 more
core
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
[Review of] Anya Peterson Royce. Ethnic Identity: Strategies for Diversity [PDF]
... Ethnic identity requires the maintenance of sufficiently consistent behavior to enable others to place an individual or group in some given social category, thus permitting appropriate interactive behavior.
Eive, Gloria
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source

