Results 151 to 160 of about 7,688 (197)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
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Journal of Environmental Psychology, 1996
This paper examines the role of place and identity processes using Breakwell's model as a framework. This model suggests that there are four principles of identity which guide action: continuity, self-esteem, self-efficacy and distinctiveness. These principles are examined here in relation to attachment to a residential environment.
Twigger-Ross, Clare L. +1 more
openaire +2 more sources
This paper examines the role of place and identity processes using Breakwell's model as a framework. This model suggests that there are four principles of identity which guide action: continuity, self-esteem, self-efficacy and distinctiveness. These principles are examined here in relation to attachment to a residential environment.
Twigger-Ross, Clare L. +1 more
openaire +2 more sources
Management Communication Quarterly, 2012
In a globalized world, place may play a much larger role in shaping occupational identities than scholars realize. Rather than serving as mere context in which identity work is conducted, cities, states, and regions are highly influential in shaping various parts of identity. This study of high-tech entrepreneurs in a city in the Rocky Mountain West of
Gregory S. Larson, Amy R. Pearson
openaire +1 more source
In a globalized world, place may play a much larger role in shaping occupational identities than scholars realize. Rather than serving as mere context in which identity work is conducted, cities, states, and regions are highly influential in shaping various parts of identity. This study of high-tech entrepreneurs in a city in the Rocky Mountain West of
Gregory S. Larson, Amy R. Pearson
openaire +1 more source
THE IDENTITY OF ARGUMENT-PLACES
The Review of Symbolic Logic, 2008Argument-places play an important role in our dealing with relations. However, that does not mean that argument-places should be taken as primitive entities. It is possible to give an account of ‘real’ relations in which argument-places play no role. But if argument-places are not basic, then what can we say about their identity? Can they, for example,
openaire +1 more source
2019
With a focus on historic sites, this volume explores the recent history of non- heteronormative Americans from the early twentieth century onward and the places associated with these communities. Authors explore how queer identities are connected with specific places: places where people gather, socialize, protest, mourn, and celebrate.
Katherine Crawford-Lackey +1 more
openaire +2 more sources
With a focus on historic sites, this volume explores the recent history of non- heteronormative Americans from the early twentieth century onward and the places associated with these communities. Authors explore how queer identities are connected with specific places: places where people gather, socialize, protest, mourn, and celebrate.
Katherine Crawford-Lackey +1 more
openaire +2 more sources