Results 71 to 80 of about 7,688 (197)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Battling the Tides of Climate Change: The Power of Intangible Cultural Resource Values to Bind Place Meanings in Vulnerable Historic Districts

Heritage, 2018
Climate change increases not only the vulnerability of cultural resources, but also the cultural values that are deeply embedded in cultural resources and landscapes.
Malorey Henderson, Erin Seekamp
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Placing Identities

MiKAN, 2012
The Pure Element of Time is an autobiographical novel, which is comprised of an especially complex network of chronotopoi. The inherently dual relationship, characteristic of any autobiography, between the “epic situation” and the narrated events, implies the very basic underlying problematics of its time/space components (i.e. of the “here” vs. “then”)
openaire   +1 more source

Place, Identity and Wellbeing: Bradford and Beyond

Internet Archaeology
This paper presents ongoing collaborative, place-based research between the University of Bradford and partner organisations, exploring the importance of identity, and the role of heritage and culture, for wellbeing, cohesion and resilience. It discusses
Karina Croucher, C. Richard Bates, Olivia Booker, Adrian Evans, Chris Gaffney, Elgidius Ichumbaki, Benjamin Jennings, Joe Moore, Joe Ogden, Joe Ritchings, Sydney Simpson, Tom Sparrow, Sharon Snaylam, Aoife Sutton-Butler, Adrian Walker, Andrew S. Wilson   +15 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Urban identity: A bibliometric review, 1969–2024

Alexandria Engineering Journal
Urban identity has global, national, local, and spatial dimensions, and its concept is multifaceted, including landmarks, history, heritage, culture, language, memory, and music.
Zaker Alesaily, Ahmed Albialy
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Optimal Experience and Personal Growth: Flow and the Consolidation of Place Identity

Frontiers in Psychology, 2016
This study examined the relationship between flow experience and place identity, based on eudaimonistic identity theory which prioritizes self-defining activities as important ones for an individual’s identification of his/her goals, values, beliefs, and
Marino Bonaiuto, Yanhui Mao, Scott Roberts, Anastasia Psalti, Silvia Ariccio, Uberta Ganucci Cancellieri, Mihaly Csikszentmihalyi   +6 more
doaj   +1 more source