Results 71 to 80 of about 5,507,680 (286)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
The Impact of Building Façade Colors on Sense of Place in a Residential Area
Wasit Journal of Engineering SciencesBuilding façade color plays a significant role in shaping urban culture, city image, and residential experiences. Yet, in many urban planning practices, the significance of building façade color is often overlooked or treated as a secondary consideration,
Avan Kareem Hamad, Hamid Turki Maliki
doaj +1 more source
Journal of ASEAN Studies, 2020 Every place on the planet has unique characters that make it distinguishable from other sites. Place-identity is the term widely accepted to explain this phenomenon.
Nyoman Gede Maha Putra +1 more
doaj +1 more source
A place in the sun : the politics of place, identity and branding
, 2008 There is no doubt that place branding is a powerful and ubiquitous practice deployed around the globe. Parallel to its acceptance and development as a distinct discipline is an understanding that place branding as responsible practice offers the means to
Mayes, Robyn
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Heritage, 2018 Climate change increases not only the vulnerability of cultural resources, but also the cultural values that are deeply embedded in cultural resources and landscapes.
Malorey Henderson, Erin Seekamp
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Place, Identity and Wellbeing: Bradford and Beyond
Internet ArchaeologyThis paper presents ongoing collaborative, place-based research between the University of Bradford and partner organisations, exploring the importance of identity, and the role of heritage and culture, for wellbeing, cohesion and resilience. It discusses
Karina Croucher +15 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source