Results 201 to 210 of about 256,488 (305)

Changing Gender Relations in Canada: The Rise of Gender-Neutral Forenames. [PDF]

Can Rev Sociol
Guppy N, Kolpashnikova K.
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Antarctic place names newly decided by the Antarctic Place-Names Committee of Japan in 1977

Antarctic Record, 1977
National Institute of Polar Research
doaj   +1 more source

Looking Beyond the Screen to Study the Technology Use of Older People Experiencing Cognitive Concerns. [PDF]

Proc SIGCHI Conf Hum Factor Comput Syst
Hu R, Choe EK, Lazar A.
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Antarctic Place Names Newly Decided by the Antarctic Place-Names Committee of Japan in 1973

Antarctic Record, 1974
NATIONAL INSTITUTE OF POLAR RESEARCH
doaj   +1 more source

Synthesised database of wild bee and hoverfly records in Europe. [PDF]

Sci Data
Sentil A, Miličić M, Benrezkallah J, Ačanski J, Andrić A, Aubert M, Bartomeus I, Biella P, Boustani M, Carstensen LB, Bogusch P, Bot S, Brau T, Budrys E, Salazar LC, Cappellari A, Carion F, Castro S, Cavaillès S, Cerretti P, Dathe HH, De Groot M, De Tandt B, Devalez J, Devorsine R, Díaz-Calafat J, Đorđević A, Dormal A, Dufrêne E, Dussaix C, Fedorova Zaytseva LA, Fiordaliso W, Flaminio S, Földesi R, Forgeois V, Gadoum S, Garrin M, Gaspar H, Gazzea E, Geppert C, Gérard M, Geslin B, Ghisbain G, Gibernau M, Grković A, Heimburg H, Herinckx A, Demeter I, Janković Milosavljević M, Janssen K, Kasparek M, Kierat J, Kleijn D, Kuhlmann M, Lair X, Lemaire S, Lenzi L, Likov L, Litman J, Lopes SB, Loureiro J, Maarten J, Maestracci PY, Marini L, Maritano U, Mei M, Mignot M, Stojnić SM, Nedeljković Z, Ockermueller E, Ortiz-Sanchez FJ, Patiny S, Paukkunen J, Pennards G, Perrard A, Petanidou T, Popov G, Popov S, Potts SG, Prokhorov A, Pruner S, Radchenko V, Radenković S, Rasmont P, Reverté S, Ricarte A, Rojo S, Romig T, Rosa P, Ruiz C, Sagot P, Santerre R, Scheper J, Selis M, Sgolastra F, Shparyk V, Siopa C, Skendžic T, Smit J, Sommaggio D, Soon V, Ssymank A, Ståhls G, Stavrinides M, Steffan-Dewenter I, Straka J, Thulier J, Tot T, Tourbez C, van Steenis J, van Steenis W, Varnava A, Veselić S, Vesnic A, Vray S, Williams P, Wood TJ, Zimmermann D, Żmuda A, Vujić A, Michez D, de Manincor N.   +121 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Details of exposure during childhood of the original children (G1s) in the ALSPAC study to aspects of religious faith and spirituality. [PDF]

Wellcome Open Res
Iles-Caven Y, Gregory S, Tohidinik HR, Golding J.   +3 more
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source