Results 121 to 130 of about 116,751 (358)

Frontiers in Nondrug Treatment of Sarcopenia: A Review of Pathological Mechanisms and the Latest Treatment Strategies

open access: yesAGING MEDICINE, EarlyView.
This article mainly introduces the pathologic process of sarcopenia and the recent progress in diagnosis and treatment, especially the nondrug treatment. ABSTRACT Sarcopenia refers to the progressive decline and wasting of skeletal muscle function, typically linked to aging or as a secondary effect of various conditions, including systemic inflammation,
Qi‐Fei Kuang   +2 more
wiley   +1 more source

Relieving acute pain (RAP) study: a proof-of-concept protocol for a randomised, double-blind, placebo-controlled trial

open access: yesBMJ Open, 2019
Introduction Physicians and other prescribing clinicians use opioids as the primary method of pain management after traumatic injury, despite growing recognition of the major risks associated with usage for chronic pain.
Thomas Scalea   +13 more
doaj   +1 more source

Salvage esophagectomy for unresectable locally advanced esophageal squamous cell carcinoma: Significant or not?

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Abstract We reviewed the current status and perspectives on salvage esophagectomy for initially unresectable locally advanced esophageal squamous cell carcinoma (ESCC) in the era of minimally invasive surgery and immunotherapy. Although the standard treatment for these patients is definitive chemoradiotherapy (CRT), the complete response rate to CRT ...
Hiroshi Saeki   +4 more
wiley   +1 more source

USO DE PLACEBOS EM PESQUISAS COM FINS COMERCIAIS: LIMITAÇÕES JURÍDICAS À LUZ DO ORDENAMENTO BRASILEIRO

open access: yesRevista de Direito Sanitário, 2016
Muito se discutem as pesquisas em seres humanos com uso de placebos sob o ponto de vista bioético, em especial à luz dos princípios bioéticos da autonomia, justiça e equidade.
Fernanda Schaefer Rivabem
doaj   +1 more source

Widespread use of pure and impure placebo interventions by GPs in Germany [PDF]

open access: yes, 2017
Aim. To collect data on the use of placebo interventions by GPs in Germany. Methods. A questionnaire was mailed to 400 randomly selected GPs in Bavaria.
Fässler, Margrit   +3 more
core  

Systemic corticosteroids for acute otitis media in children [PDF]

open access: yes, 2018
Background: Acute otitis media (AOM) is a common acute infection in children. Pain is its most prominent and distressing symptom. Antibiotics are commonly prescribed for AOM, although they have only a modest effect in reducing pain at two to three days.
Beller, Elaine M   +6 more
core   +1 more source

Genomics Review of Selective RET Inhibitors Sensitivity in Thyroid Cancer Clinical Trials

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT RET gene is a driver of thyroid cancer (TC) tumorigenesis. The incidence of TC has increased worldwide in the last few decades, both in medullary and follicular‐derived subtypes. Several drugs, including multikinase and selective inhibitors, have been explored.
Sara Gil‐Bernabé   +5 more
wiley   +1 more source

Asthma as a Model for Placebo Effects in Modern Medicine [PDF]

open access: yes, 2011
Many a clinical intervention thrives on placebos. Lack of consensus — both definitional and methodological — however, contributes to general confusion and specious conclusions regarding the legitimacy and relevance of placebos in modern medicine.
Delpero, Emily A   +2 more
core   +1 more source

Bifidobacterium animalis subsp. lactis modulates early‐life immune response and gut metabolism

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Background: The maturation of the immune system is critical during early life, as it involves the differentiation, maturation, and establishment of immune tolerance of immune cells. This process is influenced not only by genetic factors but also by environmental factors, particularly the symbiotic microbiota. Bifidobacterium animalis subsp.
Haoming Du   +17 more
wiley   +1 more source

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