Results 131 to 140 of about 484,364 (380)
Advanced Science, EarlyView.This study investigates a highly multivalent mAb platform fusing Laminin‐511 heterotrimerization domains with Fabs and IgG1‐Fc as a non‐hormonal contraceptive. The most potent molecule ‘LamH10’, possessing 10 Fabs, rapidly achieved >99% reduction in progressively motile sperm at just 33µg per dose in sheep, making the laminin‐IgG hybrid platform the ...
Alison Schaefer +8 more
wiley +1 more source
Does Inflation Targeting Matter? A Reassessment [PDF]
This paper uses a number of identification approaches (using instrumental variables, assumptions about heteroscedasticity and panel fixed effects) to estimate the effect of inflation targeting on inflation.
Luke B. Willard
core
Psychometric study of children with learning problems and 14-6 positive spike EEG patterns, treated with ethosuximide (Zarontin) and placebo. [PDF]
, 1968 W. Lynn Smith +2 more
openalex +1 more source
Advanced Science, EarlyView.The authors develop mouse models by mimicking peripheral vascular diseases, combining multiple strategies and transgenic mouse lines, to demonstrate that ECs, but not macrophages or SMCs, play an active role mediated by endothelial ET‐1/neural ETAR signaling and beyond endothelial homeostatic angiocrine by driving protective pain through the ...
Zuo‐Jie Jiang +28 more
wiley +1 more source
Annals of Gastroenterological Surgery, EarlyView.Abstract We reviewed the current status and perspectives on salvage esophagectomy for initially unresectable locally advanced esophageal squamous cell carcinoma (ESCC) in the era of minimally invasive surgery and immunotherapy. Although the standard treatment for these patients is definitive chemoradiotherapy (CRT), the complete response rate to CRT ...
Hiroshi Saeki +4 more
wiley +1 more source
Conflictos en ética de investigación con seres humanos
Cadernos de Saúde PúblicaDesde la Declaración de Helsinki 2000, se intensificó y amplió un conflictivo debate que ha cuestionado muchos aspectos de la ética de investigación con seres humanos. La polémica incluye el uso de placebos, la aplicación del concepto de equiponderación,
Miguel H. Kottow
doaj
American Journal of Hematology, EarlyView.ABSTRACTHereditary hemorrhagic telangiectasia (HHT, Osler‐Weber‐Rendu disease) is the second most common inherited bleeding disorder worldwide, affecting approximately 1 in 5000 people. Development of disease‐modifying and efficacious hemostatic agents to treat HHT has finally begun after decades without such medical therapies.
Hanny Al‐Samkari +22 more
wiley +1 more source
, 2014 This Article responds to the alarm recently sounded by the American College of Obstetricians and Gynecologists over “birth control sabotage”—the “active interference [by one partner] with [the other] partner’s contraceptive methods in an attempt to ...
Plunkett, Leah A.
core +1 more source