Results 161 to 170 of about 22,441 (303)

MDL‐800‐induced SIRT6 activation decreases age‐associated osteoarthritis in mice

Arthritis &Rheumatology, Accepted Article.
Objective SIRT6 is a nuclear‐localized histone deacetylase that regulates multiple pathways associated with aging. This study aimed to determine whether systemic administration of a small molecule activator of SIRT6, MDL‐800, decreases the severity of age‐associated osteoarthritis (OA) in mice.
Matheus Moreira Perez, Pranay Ramteke, Bahiyah Watson, Owen Haslam, Eirene Choi, Susan Chubinskaya, Mandy J. Peffers, William R. Davis, Jacqueline Shine, Brian O. Diekman, Richard F. Loeser, Theresa A. Freeman, Makarand V. Risbud, John A. Collins   +13 more
wiley   +1 more source

Placebo Effects in Modern Medicine: Mechanisms, Clinical Evidence, Limitations, and Future Directions. [PDF]

Cureus
Alnasralla MB, Nasralla BH.
europepmc   +1 more source

SAY NO TO PLACEBOS

AJN, American Journal of Nursing, 1994
Margo McCaffery, Betty R. Ferrell
openaire   +2 more sources

Early Diagnosis of Axial Spondyloarthritis Is Associated With Less Long‐Term Spinal Structural Damage: A Longitudinal Analysis of the Swiss Clinical Quality Management in Rheumatic Diseases Registry

Arthritis &Rheumatology, EarlyView.
Objective The Assessment of SpondyloArthritis international Society recently defined early axial spondyloarthritis (axSpA) as a duration of two years or less of axial symptoms. Previous studies have shown no significant difference in short‐term outcomes between patients with early and established axSpA treated with biologic/targeted synthetic disease ...
Annik Steimer, Jonas Brändli, Mauro Bachmann, Andrea Götschi, Claudia L. Rodrigues, Michael J. Nissen, Burkhard Möller, Kristina Bürki, Martin Wendiggensen, Simon Grosswiler, Michael Andor, Diana Dan, Frauke Förger, Sabine Adler, Diego Kyburz, Oliver Distler, Raphael Micheroli, Sofia Ramiro, Adrian Ciurea   +18 more
wiley   +1 more source

Open-label placebo effects on psychological distress and hair cortisol in a randomized controlled trial - the moderating role of the five-factor personality traits. [PDF]

Compr Psychoneuroendocrinol
Liedtke C, Schaefer M, Enge S.
europepmc   +1 more source

Treatment‐Driven Peripheral Blood Transcriptomic Remodeling and Baseline Predictors of ESSDAI and STAR Response to B Cell Therapy in Sjögren's Disease

Arthritis &Rheumatology, EarlyView.
Graphical Abstract Objective This study aimed to characterize whole blood transcriptomic profiles in adults with active Sjögren's disease (SjD) treated with anti‐CD20 or B lymphocyte stimulator/BAFF inhibition, identify markers of clinical response, and define inflammatory pathways linked to nonresponse. Methods Whole blood RNA sequencing was performed
Aimen Ibrahim, Junjie Peng, Eileen Tian, Lucia Martin‐Gutierrez, John Casement, Kyle Thompson, Wan‐Fai Ng, André van Maurik, Elizabeth C. Jury, Coziana Ciurtin   +9 more
wiley   +1 more source

Reframing the Performance and Ethics of Empathic AI: Wisdom of the Crowd and Placebos. [PDF]

Perspect Psychol Sci
Thornton MA.
europepmc   +1 more source

Placebos

, 1998
Brown, Walter A.
core  

Reply

Arthritis &Rheumatology, EarlyView.
Joseph F. Merola, Cynthia E. Kartman, Peter Fischer, Luna Sun, Anabela Cardoso, Mark C. Genovese, Alexis Ogdie   +6 more
wiley   +1 more source

Effects of Cannabidiol‐Rich Cannabis Oil on Facial Expression Recognition and Theory of Mind in Children With Autism Spectrum Disorder: A Randomized Clinical Trial

Autism Research, EarlyView.
ABSTRACT To evaluate, in a post hoc subanalysis, the effects of cannabidiol (CBD)‐rich cannabis oil on facial expression recognition and theory of mind in children with autism spectrum disorder (ASD). This post hoc subanalysis included children from a double‐blind, randomized, placebo‐controlled trial who completed social cognition assessments at ...
Wandersonia Moreira Brito Medeiros, Estácio Amaro da Silva Junior, Katy Lísias Gondim Dias de Albuquerque, Marine Diniz da Rosa, Amanda Gleiciane de Lima Oliveira, Maycon Jônatas da Silva, João Vitor Andrade Fernandes, Emily Caroline Costa Vieira, João Paulo Mendes dos Santos, Thais Cavalcanti Borges, Ana Hermínia Andrade e Silva, Carlos Espínola Neto Segundo, Nelson Torro‐Alves   +12 more
wiley   +1 more source