Results 191 to 200 of about 114,609 (356)

Positive messages may reduce patient pain: A meta-analysis [PDF]

open access: yes, 2017
Introduction Current treatments for pain have limited benefits and worrying side effects. Some studies suggest that pain is reduced when clinicians deliver positive messages.
Howick, Jeremy, Mebius, Alexander
core  

EFEITO PLACEBO - IMPLICAÇÕES PARA A ASSISTÊNCIA E O ENSINO DE ENFERMAGEM

open access: yesRevista da Escola de Enfermagem da USP
As autoras fazem uma revisão bibliográfica sobre o placebo e o efeito placebo, enfocando sua conceituação, histórico, tipos, ação, indicações e características da placebo reator, para fundamentar as implicações do seu uso e efeitos para o ensino e a ...
Miriam Aparecida Barbosa Merighi   +2 more
doaj   +1 more source

Lecanemab‐Associated Amyloid‐β Protofibril in Cerebrospinal Fluid Correlates with Biomarkers of Neurodegeneration in Alzheimer's Disease

open access: yesAnnals of Neurology, EarlyView.
Objective The Clarity AD phase III trial showed that lecanemab reduced amyloid markers in early Alzheimer's disease (AD) and resulted in less decline on measures of cognition and function than placebo. Herein, we aimed to characterize amyloid‐β (Aβ) protofibril (PF) captured by lecanemab in human cerebrospinal fluid (CSF) from living participants with ...
Moeko Noguchi‐Shinohara   +8 more
wiley   +1 more source

PLACEBO

open access: bronze, 1957

openalex   +1 more source

Brain Metabolic Features of FUS‐ALS: A 2‐[18F]FDG‐PET Study

open access: yesAnnals of Neurology, EarlyView.
Objective We aimed at evaluating the brain metabolic features of fused in sarcoma amyotrophic lateral sclerosis (FUS‐ALS) compared with sporadic ALS (sALS), using 2‐[fluorine‐18] fluoro‐2‐deoxy‐D‐glucose positron emission tomography (2‐[18F]FDG‐PET). Methods We employed the 2‐sample t‐test model of SPM12, implemented in MATLAB, to compare 12 FUS‐ALS ...
Antonio Canosa   +24 more
wiley   +1 more source

Interleukin 6/gp130 axis promotes neural invasion in pancreatic cancer

open access: yesCancer Medicine, Volume 11, Issue 24, Page 5001-5012, December 2022., 2022
Nerve invasion (N‐inv) is an important prognostic factor in pancreatic ductal adenocarcinoma (PDAC). To elucidate circulating stimulators for nerve invasion, the authors evaluated the stimulant activity and the inhibitory effects of IL‐6/gp130 axis. Biological activity of IL‐6/gp130 axis promoted nerve invasion in murine model and was upregulated in ...
Hidetaka Suzuki   +9 more
wiley   +1 more source

Plasma Glucosylceramide Levels Are Regulated by ATP10D and Are Not Involved in Parkinson's Disease Pathogenesis

open access: yesAnnals of Neurology, EarlyView.
GBA1 variants and decreased glucocerebrosidase activity are implicated in Parkinson's disease (PD). We investigated the hypothesis that increased levels of glucosylceramide (GlcCer), a main substrate of glucocerebrosidase, are involved in PD pathogenesis.
Emma N. Somerville   +13 more
wiley   +1 more source

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