Results 191 to 200 of about 116,751 (358)

A comparative trial of clonidine, propranolol and placebo in the treatment of moderate hypertension. [PDF]

, 1977
P. Wilkinson, E. B. Raftery
openalex   +1 more source

Appraising the visibility, relevance and impacts of clinical pharmacology

British Journal of Clinical Pharmacology, EarlyView.
Aims Clinical pharmacology (CP) used to be a strong medical and scientific field, but during the last three decades it seems to have lost some of its appeal. We reviewed the visibility, relevance and impact of CP and clinical pharmacologists across the globe and suggest ways to strengthen the discipline to address future pharmacotherapeutic challenges.
Serge Cremers, Samuel L. M. Arnold, Nilima A. Kshirsagar, Catriona Waitt, Olayinka O. Ogunleye, Lars L. Gustafsson   +5 more
wiley   +1 more source

Homeopathy and placebo - Synonym, similar or different? [PDF]

, 2007
Meissner, Karin, Zimmermann-Viehoff, Frank   +1 more
core   +1 more source

A PLACEBO‐CONTROLLED COMPARISON OF THE SEDATIVE PROPERTIES OF THREE BENZODIAZEPINES, LORAZEPAM, FLUNITRAZEPAM AND FOSAZEPAM [PDF]

, 1977
J. W. Dundee, H.M.L. JOHNSTON, J.K. LILBURN, S.G. NAIR, Michael Scott   +4 more
openalex   +1 more source

Management of hypotension in dihydropyridine calcium channel blocker overdose: The role of high‐dose insulin therapy

British Journal of Clinical Pharmacology, EarlyView.
Aims Amlodipine poisoning is a leading cause of cardiovascular medication‐related deaths, commonly managed with high‐dose insulin (HDI) therapy. However, HDI is a vasodilator that is counterproductive in managing vasoplegia. We aim to study HDI therapy in patients with hypotension following dihydropyridine calcium channel antagonist (CCA) overdose ...
Betty S. H. Chan, Katherine Z. Isoardi, Darren M. Roberts, Ong Sook Har   +3 more
wiley   +1 more source

Materials for Placebo V.

, 1966
W. C. Watt
openalex   +1 more source

A Comparison of Betahistine Hydrochloride With Placebo for Vertebral-Basilar Insufficiency: A Double-Blind Study [PDF]

, 1975
JAMES H. SPRUILL, James F. Toole, William Kitto, Hersey E. Miller   +3 more
openalex   +1 more source

Sentinel dosing: A proposed algorithm to guide decision making on which cohorts in early phase clinical pharmacology trials should use this approach

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The aim of this paper is to describe a proposal for an algorithm to guide decision making on which cohorts in early phase pharmacology trials should employ a sentinel approach, thereby standardising and harmonising practices, and improving decision making around sentinel dosing.
Jules A. A. C. Heuberger, Perry de Jongh, Ewoud‐Jan van Hoogdalem, Wim Tamminga, Pieter de Graeff, Geert Jan Groeneveld   +5 more
wiley   +1 more source

Pharmacokinetics and pharmacodynamics of empagliflozin in paediatric patients aged 10–17 years with type 2 diabetes mellitus

British Journal of Clinical Pharmacology, EarlyView.
Aims To characterize the pharmacokinetics (PK) and PK/pharmacodynamics (PD) regarding glycosylated haemoglobin (HbA1c) lowering using the paediatric data from DINAMO and to assess differences compared with adults. Methods Population PK and PK/PD models previously developed for empagliflozin in adults and adolescents were re‐estimated in a Bayesian ...
Juliane Rascher, Shen Cheng, Curtis Johnston, Sebastian Härtter, Wojtyniak Jan‐Georg, Jan Marquard, Igor Tartakovsky, Lori M. B. Laffel   +7 more
wiley   +1 more source

A Placebo-Controlled Double-Blind Crossover Investigation of the Side Effects Attributed to Oral Contraceptives

, 1971
Joseph W. Goldzieher, Louis E. Moses, E. G. Averkin, Cora Scheel, Ben Z. Taber   +4 more
openalex   +1 more source