Results 201 to 210 of about 122,680 (303)

A systematic qualitative review of ethical issues in open label placebo in published research. [PDF]

Sci Rep
Richard M, Bernstein M, Gaab J, Elger B.
europepmc   +1 more source

Epirubicin for the Treatment of Sepsis and Septic Shock (EPOS-1): study protocol for a randomised, placebo-controlled phase IIa dose-escalation trial [PDF]

Daniel Thomas‐Rüddel, Michael Bauer, Luís F. Moita, Christiane Helbig, Peter Schlattmann, Johannes Ehler, Tim Rahmel, Patrick Meybohm, Matthias Gründling, Heiko Schenk, Thomas Köcher, Frank M. Brunkhorst, Markus H. Gräler, Ann-Julika Heger, Sebastian Weis   +14 more
openalex   +1 more source

The Effect of Benralizumab and Mepolizumab on Use of Oral Glucocorticoids in Patients With Eosinophilic Granulomatosis With Polyangiitis

Arthritis &Rheumatology, EarlyView.
Objective The phase 3 MANDARA study demonstrated noninferiority of benralizumab versus mepolizumab for remission in patients with eosinophilic granulomatosis with polyangiitis (EGPA). More benralizumab‐treated patients achieved complete withdrawal of oral glucocorticoids (OGCs).
Parameswaran K. Nair, Bernhard Hellmich, Arnaud Bourdin, David R. W. Jayne, Florence Roufosse, Nader Khalidi, Lena Börjesson Sjö, Ying Fan, Christopher McCrae, Sofia Necander, Eva Rodríguez‐Suárez, Anat Shavit, Claire Walton, Peter A. Merkel, Michael E. Wechsler   +14 more
wiley   +1 more source

Methodological considerations for the Lianhua Qingwen capsule influenza prevention trial. [PDF]

J Thorac Dis
Xue C, Chen J.
europepmc   +1 more source

High-Dose Probiotic Mix of Lactobacillus Spp, Bifidobacterium Spp, Bacillus coagulans, and Saccharomyces boulardii to Prevent Antibiotic-Associated Diarrhea in Adults: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial (SPAADA) [PDF]

Cynthia Isabel Ortiz-Lopez, Adrián Camacho-Ortíz   +1 more
openalex   +1 more source

Sjögren Disease—B Cells at the Brink: From Autoimmunity to Lymphomagenesis and the Rise of Novel B Cell‐Targeted Therapies

Arthritis &Rheumatology, Accepted Article.
Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no FDA‐approved disease‐modifying therapies for SjD.
Rachael A. Gordon, Sara S. McCoy
wiley   +1 more source

Public and professional attitudes towards deceptive and open-label placebo in functional neurological disorder and wider neurological practice. [PDF]

BMJ Neurol Open
Huys AML, Bhatia KP, Edwards MJ.
europepmc   +1 more source

Tofacitinib for the Treatment of Juvenile Idiopathic Arthritis: Patient‐Reported Outcomes in a Phase 3, Randomized, Double‐Blind, Placebo‐Controlled Withdrawal Trial

Arthritis &Rheumatology, EarlyView.
Objective Juvenile idiopathic arthritis (JIA) is associated with impaired overall health‐related quality of life (HRQoL). We evaluated the impact of tofacitinib on patient‐reported outcomes (PROs) in patients with JIA. Methods This was a post hoc analysis of a phase 3, randomized, double‐blind, placebo‐controlled withdrawal trial (NCT02592434) in ...
Hermine I. Brunner, Ekaterina Alexeeva, Marcia Bandeira, Ruy Carrasco, Jeffrey Chaitow, Peter Chiraseveenuprapund, Tracy V. Ting, Muferet Erguven, Beth Gottlieb, Sheila Knupp Oliveira, Pooja N. Patel, Seza Ozen, Claudia Saad Magalhaes, Inmaculada Calvo Penadés, David Gruben, Rebecca Germino, Holly B. Posner, Lori Stockert, Alberto Martini, Daniel J. Lovell, Nicolino Ruperto, for the Paediatric Rheumatology International Trials Organisation (PRINTO) and Pediatric Rheumatology Collaborative Study Group (PRCSG)   +21 more
wiley   +1 more source

Addressing blinding in classic psychedelic studies with innovative active placebos. [PDF]

Int J Neuropsychopharmacol
Aday JS, Simonsson O, Schindler EAD, D'Souza DC.   +3 more
europepmc   +1 more source

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Arthritis &Rheumatology, EarlyView.
Spencer I. Danto, Elena Peeva
wiley   +1 more source