Results 241 to 250 of about 484,364 (380)

Reply

Arthritis &Rheumatology, EarlyView.
Spencer I. Danto, Elena Peeva
wiley   +1 more source

Mild psoriasis as a suitable model for proof‐of‐mechanism in a phase 1B setting: Results from a double‐blind placebo‐controlled trial with guselkumab

British Journal of Clinical Pharmacology, EarlyView.
Aims Early clinical development of novel psoriasis therapies is hampered by a decreasing number of moderate‐to‐severe psoriasis patients eligible for participation in trials since efficacious treatments, such as biologics, have become widely available.
Jannik Rousel, Menthe E. Bergmans, Lisa J. Bruijnincx, Sissi Lin, Tessa Niemeyer‐van der Kolk, Roman Bohoslavsky, Yalçin Yavuz, Naomi B. Klarenbeek, Joke A. Bouwstra, Robert Rissmann, Martijn B. A. van Doorn, the Next‐Generation ImmunoDermatology Consortium (NGID)   +11 more
wiley   +1 more source

Conditioned open-label placebos to facilitate opioid reduction in patients with chronic non-cancer pain: study protocol of a randomised controlled trial. [PDF]

BMJ Open
Carratta K, Bodonyi K, Frey Nascimento A, Friis D, von Känel R, Bircher L, Koechlin H, Bernstein M, Streitberger K, Arnet I, Roth AJ, Ronel J, Olliges E, Locher C.   +13 more
europepmc   +1 more source

A Comparison of Betahistine Hydrochloride With Placebo for Vertebral-Basilar Insufficiency: A Double-Blind Study

, 1975
JAMES H. SPRUILL, James F. Toole, William Kitto, Hersey E. Miller   +3 more
openalex   +1 more source

Treatment of Men with Idiopathic Oligozoospermic Infertility Using the Aromatase Inhibitor, Testolactone Results of a Double‐Blinded, Randomized, Placebo‐Controlled Trial with Crossover [PDF]

, 1989
Richard V. Clark, Richard J. Sherins
openalex   +1 more source

Combination vs. single‐drug nonprescription analgesics for acute pain management: A narrative review

British Journal of Clinical Pharmacology, EarlyView.
Combining nonprescription analgesics with different mechanisms of action has been proposed as a rational strategy to optimize the management of acute pain. This review assessed the efficacy and safety of nonprescription analgesics, including paracetamol (acetaminophen), metamizole and nonsteroidal anti‐inflammatory drugs (NSAIDs) used in combination vs.
Ali Mobasheri, Bart Morlion, Vidhu Sood Sethi, Mary Cardosa, Oscar Della Pasqua, Pranab Kalita   +5 more
wiley   +1 more source

Acute and prolonged toxicity assessment of Cannabis sativa extract in rodents and lagomorphs. [PDF]

Toxicol Rep
Costa AC, Gasparotto A, Garcia AAK, Pereira CAC, Lourenço ELB, Joaquim HPG.   +5 more
europepmc   +1 more source

The Relationship Between “Rapid Induction” and Placebo Analgesia, Hypnotic Susceptibility, and Chronic Pain Intensity

, 1978
Lorraine Snow
openalex   +2 more sources

Efficacy and safety of a selective partial agonist for nociception/orphanin‐FQ peptide (NOP) receptors in patients with insomnia disorder

British Journal of Clinical Pharmacology, EarlyView.
Aims Insomnia is a common sleep disorder, affecting up to 20% of the world population and adversely impacting productivity, health, and overall well‐being. Although pharmacologic options exist to treat insomnia, the health‐related quality of life for patients who are prescribed hypnotics is no higher than for those who are not, revealing a significant ...
Garth T. Whiteside, Ellie He, S. Shet Manjunath, Mingyan Zhou, Maha Ahmad, Stephen C. Harris   +5 more
wiley   +1 more source

Matching placebo development for injectable biologics-a practical tutorial. [PDF]

Antib Ther
Xin L, Zhang Z, Shah K, Hashemi V, Li X, Qin G, Ren S, Chen W, Li Y.   +8 more
europepmc   +1 more source