Results 301 to 310 of about 114,609 (356)

Caffeine Placebo Effect in Sport and Exercise: A Systematic Review. [PDF]

open access: yesNutrients
Vega-Muñoz A   +5 more
europepmc   +1 more source

Deciphering the transcriptomic landscape of early HR+/HER2− breast cancer in very young women

open access: yes
Cancer Communications, EarlyView.
Iris Garrido‐Cano   +15 more
wiley   +1 more source

Target‐Mediated Modeling of Alirocumab in Adolescents and Children ≥8 to <12 Years of Age Using Phase II and III Data

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract A population pharmacokinetic (PK) covariate analysis was conducted utilizing data from adolescents and children ≥8 to <12 years of age with heterozygous familial hypercholesterolemia. One phase II and 1 phase III study were analyzed (121 patients on active treatment).
Pavel Kovalenko   +5 more
wiley   +1 more source

A Systematic Review of Study Design and Placebo Controls in Psychedelic Research. [PDF]

open access: yesPsychedelic Med (New Rochelle)
Wen A   +8 more
europepmc   +1 more source

A Phase 1C, Open Label, Single Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of DM199 Administered Intravenously with a Polyvinyl Chloride Bag in Adult Healthy Subjects and Adults Recently Taking Angiotensin‐Converting Enzyme Inhibitors

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract This small phase 1C, open‐label, single ascending dose study evaluated the safety, tolerability, and pharmacokinetics (PKs) of DM199, a recombinant form of human tissue kallikrein‐1 (KLK1). A small sample size of both healthy subjects and hypertensive adults recently taking angiotensin‐converting enzyme inhibitors was studied. KLK1 has a known
Michael Giuffre   +3 more
wiley   +1 more source

Acute Effects and Pharmacokinetics of LSD after Paroxetine or Placebo Pre‐Administration in a Randomized, Double‐Blind, Cross‐Over Phase I Trial

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Psychedelics, such as psilocybin and lysergic acid diethylamide (LSD), are being investigated for the treatment of depressive and anxiety disorders, for which concomitant treatment with selective serotonin reuptake inhibitors (SSRIs) is prevalent.
Anna M. Becker   +12 more
wiley   +1 more source

Placebo and the law of identification. [PDF]

open access: yesFront Psychiatry
Bierman SF, Weil A, Dahmer S.
europepmc   +1 more source

Placebo

open access: yesForum Médical Suisse ‒ Swiss Medical Forum, 2007
openaire   +1 more source

A Benchmark, Expand, and Calibration (BenchExCal) Trial Emulation Approach for Using Real‐World Evidence to Support Indication Expansions: Design and Process for a Planned Empirical Evaluation

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Real‐world evidence involving healthcare database studies is well established for making causal inferences in post‐market drug safety studies and methods, data, and research infrastructure for evaluating effectiveness have advanced in recent years. The rapidly expanding field of etiologic research using insurance claims and electronic health records ...
Shirley V. Wang   +6 more
wiley   +1 more source

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