Results 91 to 100 of about 2,377,907 (274)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Schizophrenia and schizoaffective disorder: Length of stay and associated factors

South African Journal of Psychiatry
Background: Patients with schizophrenia and schizoaffective disorder often require longer admissions. Aim: To explore length of stay (LOS) and associated factors of patients with schizophrenia and schizoaffective disorder, admitted to a public sector ...
Ladawa Y. Goga, Belinda S. Marais
doaj   +1 more source

Les enfants autochtones en protection de la jeunesse au Québec : leur réalité comparée à celle des autres enfants

Criminologie, 2012
Les recherches canadiennes et internationales s’entendent sur la surreprésentation des enfants autochtones en protection de l’enfance. La présente étude ajoute aux connaissances sur les mauvais traitements et la réponse des services de protection de la ...
Alexandra Breton, Sarah Dufour, Chantal Lavergne   +2 more
doaj   +1 more source

Providing work Placements for disabled students : a good practice guide for further and higher education institutions [PDF]

, 2002
"This document provides a guide to institutions’ duties in regard to work placements and offers practical advice on what institutions can do to ensure quality work placement opportunities for disabled students.

core  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Taking a Cross-Faculty Stand Against Racism and Inequality: What Are Enabling and Inhibiting Factors Influencing the Placement Experiences of Black, Asian, Ethnic Minoritised Students in the Schools of Social Work, Education, and Health Sciences?

Genealogy
Many Black, Asian, and ethnic minoritised students on university courses leading to professional qualifications face racism on placement. Our own institutional review at one UK university highlighted differential placement outcomes for students in the ...
Carlene Cornish, Stephanie T. Jong, Isabella Albarran, Swati Kale, Sarah Brownsword, Cat Playfair, Sophie Vauzour, Tina Odu, Godfrey Lusigi, Virginia Shikuku   +9 more
doaj   +1 more source

Credit Bearing Undergraduate Placements – Should We or Shouldn’t We? Staff and Student Perspectives [PDF]

, 2016
A credit bearing placement, in lieu of a dissertation, has been offered as an option on the environmental undergraduate programme at the School of Interdisciplinary Studies (University of Glasgow) since 2001.
Mackie, Rebecca, Wood, Bethan
core  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

« J’habite… enfin…, je me comprends » : l’appropriation territoriale des adolescents placés en question

Enfances, Familles, Générations, 2013
The connection with adolescent space and, more specifically, its mobility, is often comprehended through the framework of the family and of a single residential location.
Fleur Guy
doaj