Results 101 to 110 of about 725,003 (400)
Bioprinted Constructs in the Regulatory Landscape: Current State and Future Perspectives
Advanced Materials, EarlyView.Bioprinting has rapidly emerged as a transformative technology in biomedical research, offering unprecedented potential to replicate complex tissues. Despite its promise, clinical translation remains limited due to regulatory hurdles. This review explores global regulatory frameworks, comparing approaches in the EU, U.S., China, and Australia, and ...
Francesca Perin +6 more
wiley +1 more source
Advance in placenta drug delivery: concern for placenta-originated disease therapy
Drug Delivery, 2023 In the therapy of placenta-originated diseases during pregnancy, the main challenges are fetal exposure to drugs, which can pass through the placenta and cause safety concerns for fetal development. The design of placenta-resident drug delivery system is
Miao Tang +8 more
doaj +1 more source
Transport of persistent organic pollutants across the human placenta [PDF]
, 2014 Environment International 65, 107-115 ...
Fernández-Somoano, A +9 more
core +1 more source
Nanostructured Protein Surfaces Inspired by Spider Silk
Advanced Materials, EarlyView.Harnessing recombinant spider silk technology, bioengineered spidroin variants enable the creation of functionalized nanostructured coatings with tunable affinity for specific targets, supporting a broad range of applications ‐ from antifouling surfaces and targeted drug delivery to advanced cell therapies and precision bio‐patterning via lithography ...
Martin Humenik, Thomas Scheibel
wiley +1 more source
Early onset preeclampsia is characterized by altered placental lipid metabolism and a premature increase in circulating FABP4 [PDF]
, 2010 Preeclampsia is a pregnancy-associated disorder that manifests as a sudden increase in maternal blood pressure accompanied by proteinuria. Because the placenta is a key organ in preeclampsia, we used proteomic and lipidomic analyses to compare placentae ...
Aaron Booy +5 more
core +1 more source
Placental-mediated increased cytokine response to lipopolysaccharides: a potential mechanism for enhanced inflammation susceptibility of the preterm fetus. [PDF]
, 2012 BackgroundCerebral palsy is a nonprogressive motor impairment syndrome that has no effective cure. The etiology of most cases of cerebral palsy remains unknown; however, recent epidemiologic data have demonstrated an association between fetal neurologic ...
Belkacemi, Louiza +4 more
core +1 more source
Advanced Materials Interfaces, EarlyView.This study confirms that extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs) or HEK293F cells overexpressing CD24 have anti‐inflammatory effects in macrophages and monocytes. Further loading either of these EVs with an anti‐Myd88 peptide synergistically enhanced the anti‐inflammatory effects of the EVs.
Burçin İrem Abas +6 more
wiley +1 more source
Placenta Accreta Spectrum: A Review of Pathology, Molecular Biology, and Biomarkers
Disease Markers, 2018 Background. Placenta accreta spectrum (PAS) is a condition of abnormal placental invasion encompassing placenta accreta, increta, and percreta and is a major cause of severe maternal morbidity and mortality. The diagnosis of a PAS is made on the basis of
H. Bartels +3 more
semanticscholar +1 more source
Best Practice & Research Clinical Obstetrics & Gynaecology, 2008 The retained placenta is a significant cause of maternal mortality and morbidity throughout the developing world. It complicates 2% of all deliveries and has a case mortality rate of nearly 10% in rural areas. Ultrasound studies have provided fresh insights into the mechanism of the third stage of labour and the aetiology of the retained placenta ...
openaire +5 more sources
Advanced Materials Technologies, EarlyView.Thermal annealing improves the structure, stiffness, and piezoelectric properties of poly(vinylidene flouride‐trifluoroethylene) (PVDF‐TrFE) nanofiber scaffolds. These annealed scaffolds promote Schwann cell proliferation and matrix remodeling in vitro and demonstrate in vivo biocompatibility.
Maksym Krutko +12 more
wiley +1 more source