Results 101 to 110 of about 742,957 (396)

Plasticenta: First evidence of microplastics in human placenta.

Environment International, 2021
A. Ragusa, A. Svelato, C. Santacroce, Piera Catalano, V. Notarstefano, O. Carnevali, F. Papa, M. Rongioletti, F. Baiocco, Simonetta Draghi, Elisabetta D’Amore, Denise Rinaldo, Maria Matta, E. Giorgini   +13 more
semanticscholar   +1 more source

Prenatal ultrasound staging system for placenta accreta spectrum disorders

Ultrasound in Obstetrics and Gynecology, 2019
To develop a prenatal ultrasound staging system for placenta accreta spectrum (PAS) disorders in women with placenta previa and to evaluate its association with surgical outcome, placental invasion and the clinical staging system for PAS disorders ...
G. Calỉ, F. Forlani, C. Lees, C. Lees, C. Lees, I. Timor-Tritsch, J. Palacios-Jaraquemada, A. Dall'asta, A. Dall'asta, A. Dall'asta, A. Bhide, M. E. Flacco, L. Manzoli, F. Labate, A. Perino, G. Scambia, F. D'antonio   +16 more
semanticscholar   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

Maternal zinc intakes and homeostatic adjustments during pregnancy and lactation. [PDF]

, 2012
Zinc plays critical roles during embryogenesis, fetal growth, and milk secretion, which increase the zinc need for pregnancy and lactation. Increased needs can be met by increasing the dietary zinc intake, along with making homeostatic adjustments in ...
Donangelo, Carmen, King, Janet
core   +2 more sources

Placenta Accreta Spectrum: A Review of Pathology, Molecular Biology, and Biomarkers

Disease Markers, 2018
Background. Placenta accreta spectrum (PAS) is a condition of abnormal placental invasion encompassing placenta accreta, increta, and percreta and is a major cause of severe maternal morbidity and mortality. The diagnosis of a PAS is made on the basis of
H. Bartels, James Postle, P. Downey, D. Brennan   +3 more
semanticscholar   +1 more source

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

Advanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao, Yijun Zhang, Hanyu Rao, Jiani Sun, Zhiyi Pan, Liping Jin, Yan Zhao   +6 more
wiley   +1 more source

The Human Pregnancy-Specific Glycoprotein Genes are Tightly Linked on the Long Arm of Chromosome 19 and are Coordinately Expressed [PDF]

, 1990
The pregnancy-specific glycoprotein (PSG) genes encode a group of proteins which are found in large amounts in placenta and maternal serum. In situ hybridization analyses of metaphase chromosomes reveal that all the human pregnancy-specific glycoprotein (
Barnett, Barnett, Barnett, Benton, Bohn, Chan, Chomczynski, Feinberg, Fiddes, Grunert, Hefta, Hinoda, Jean, Kamarck, Khan, Khan, Kolbinger, Lathe, Lin, Maniatis, Neumaier, Niemann, Oikawa, Oikawa, Oikawa, Paxton, Perry, Rooney, Rudert, Sanger, Streydio, Takami, Tatarinov, Thompson, Thompson, Thompson, Watanabe, Watanabe, Willcocks, Zimmermann, Zimmermann   +40 more
core   +1 more source

Lack of detection of a human placenta microbiome in samples from preterm and term deliveries

Microbiome, 2018
Historically, the human womb has been thought to be sterile in healthy pregnancies, but this idea has been challenged by recent studies using DNA sequence-based methods, which have suggested that the womb is colonized with bacteria. For example, analysis
Jacob S. Leiby, K. McCormick, S. Sherrill-Mix, Erik L. Clarke, Lyanna R. Kessler, Louis J. Taylor, C. Hofstaedter, A. Roche, Lisa M. Mattei, K. Bittinger, M. Elovitz, R. Leite, S. Parry, F. Bushman   +13 more
semanticscholar   +1 more source

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

Improving diagnosis in patients with obstetric antiphospholipid syndrome through the evaluation of non‐criteria antibodies

Clinical & Translational Immunology
Objectives Antiphospholipid syndrome (APS) is an autoimmune disease driven by antiphospholipid antibodies (aPL). Currently, APS diagnosis requires a combination of clinical manifestations (thrombosis and/or obstetric morbidity) and the persistent ...
Daniel Álvarez, Hephzibah E Winter, Carlos J Velasquez Franco, Aleida Susana Castellanos Gutierrez, Núria Baños, Udo R Markert, Ángela P Cadavid, Diana M Morales‐Prieto   +7 more
doaj   +1 more source