Morphology and physiology of rat placenta for toxicological evaluation
Journal of Toxicologic Pathology, 2018 The placenta plays a pivotal role in fetal growth, and placental dysfunction and injury are associated with embryo/fetal toxicity. Histological examination of the rat placenta for safety evaluation provides valuable clues to the mechanisms of this ...
S. Furukawa, Naho Tsuji, A. Sugiyama
semanticscholar +1 more source
Laeverin is Cell‐Surface Target for Liquid‐Phase Metastasizing Cancer Cells
Advanced Science, EarlyView.This study revealed that epithelial cancer cells in the floating phase induce the expression of laeverin (LVRN) that is a trophoblast‐specific and cell‐surface immunoregulatory factor and showed that anti‐LVRN ADC is a promising agent that can attack cancer cells in the metastatic liquid phase and block further distant metastasis.
Haruki Kasama +17 more
wiley +1 more source
Neutralizing Monoclonal Antibodies Reduce Human Cytomegalovirus Infection and Spread in Developing Placentas. [PDF]
, 2019 Congenital human cytomegalovirus (HCMV) infection is a leading cause of birth defects worldwide, yet the most effective strategies for preventing virus transmission during pregnancy are unknown.
An, Zhiqiang +8 more
core +1 more source
Establishment and differentiation of long-term trophoblast organoid cultures from the human placenta
Nature Protocols, 2018 The human placenta is essential for successful reproduction. There is great variation in the anatomy and development of the placenta in different species, meaning that animal models provide limited information about human placental development and ...
M. Sheridan +6 more
semanticscholar +1 more source
Chronic PET‐Microplastic Exposure: Disruption of Gut–Liver Homeostasis and Risk of Hepatic Steatosis
Advanced Science, EarlyView.Chronic exposure to environmentally relevant PET microplastics disrupts gut–liver homeostasis, leading to hepatic steatosis, early fibrosis, and altered gut microbiota. These effects signal metabolic imbalance and gut–liver axis impairment, emphasizing chronic microplastic ingestion as an emerging environmental health risk linked to non‐communicable ...
Surye Park +5 more
wiley +1 more source
Reproductive outcomes following induced abortion : a national register-based cohort study in Scotland [PDF]
, 2012 PMID: 22869092 [PubMed] Free full textPeer ...
Bhattacharya, Siladitya +6 more
core +2 more sources
Development of the Human Placenta and Fetal Heart: Synergic or Independent?
Frontiers in Physiology, 2018 The placenta is the largest fetal organ, and toward the end of pregnancy the umbilical circulation receives at least 40% of the biventricular cardiac output.
G. Burton, E. Jauniaux
semanticscholar +1 more source
The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia
Advanced Science, EarlyView.The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo +3 more
wiley +1 more source
Advanced Science, EarlyView.Folic acid (FA) and multivitamins/minerals (MVM) are recommended for the prevention of neural tube defects (NTDs). Using a novel human neural tube‐like organoid system and mouse models, the study compares the effectiveness of two supplements on NTDs and cellular behaviors.
Huili Li +3 more
wiley +1 more source
“Hand as foot” teaching method in placenta previa
, 2021 Jia Liu, Jiandong Song, Rina Sa, Rui Liu
openalex +1 more source