Results 121 to 130 of about 725,003 (400)

Plasticenta: First evidence of microplastics in human placenta.

open access: yesEnvironment International, 2021
A. Ragusa   +13 more
semanticscholar   +1 more source

Deciphering the Role and Mechanism of Decidual Monocyte‐Derived Macrophage Infiltration in Obstetric Antiphospholipid Syndrome at Single‐Cell Resolution

open access: yesAdvanced Science, EarlyView.
This study uncovers a novel mechanism and therapeutic targets in obstetric antiphospholipid syndrome (OAPS). Antiphospholipid antibody/ß2‐glycoprotein I complex boosts CCL2 and TNF‐α expression in decidual macrophages via TLR4‐NF‐κB. CCL2 accumulates on endothelial surfaces via ACKR1, recruiting monocyte‐derived CCR2+ macrophages, driving inflammation,
Rui Gao   +13 more
wiley   +1 more source

Factores de riesgo de placenta previa en mujeres embarazadas en un hospital de República Dominicana

open access: yesCiencia y Salud, 2020
Introducción: la hemorragia obstétrica es una de las causas de morbilidad y mortalidad materna más común en todo el mundo. La placenta previa es un factor de riesgo importante para la hemorragia obstétrica.
Laura Manosalvas   +5 more
doaj   +1 more source

A lesson for cancer research : placental microarray gene analysis in preeclampsia [PDF]

open access: yes, 2012
Tumor progression and pregnancy share many common features, such as immune tolerance and invasion. The invasion of trophoblasts in the placenta into the uterine wall is essential for fetal development, and is thus precisely regulated.
Louwen, Frank   +4 more
core   +2 more sources

Lack of detection of a human placenta microbiome in samples from preterm and term deliveries

open access: yesMicrobiome, 2018
Historically, the human womb has been thought to be sterile in healthy pregnancies, but this idea has been challenged by recent studies using DNA sequence-based methods, which have suggested that the womb is colonized with bacteria. For example, analysis
Jacob S. Leiby   +13 more
semanticscholar   +1 more source

ADAR1 as a Placental Innate Immune Rheostat Sustaining the Homeostatic Balance of Intrinsic Interferon Response at the Maternal‐Fetal Interface

open access: yesAdvanced Science, EarlyView.
This study reveals that ADAR1, an RNA‐editing enzyme, fine‐tunes immune responses in the placenta by preventing the accumulation of immunogenic double‐stranded RNAs (dsRNAs) from interferon‐stimulated genes. The loss of ADAR1 in the placenta leads to excessive interferon signaling restricted to the junctional zone, disrupting placental development and ...
Xiaogang Chen   +7 more
wiley   +1 more source

Improving diagnosis in patients with obstetric antiphospholipid syndrome through the evaluation of non‐criteria antibodies

open access: yesClinical & Translational Immunology
Objectives Antiphospholipid syndrome (APS) is an autoimmune disease driven by antiphospholipid antibodies (aPL). Currently, APS diagnosis requires a combination of clinical manifestations (thrombosis and/or obstetric morbidity) and the persistent ...
Daniel Álvarez   +7 more
doaj   +1 more source

Molar pregnancy and co-existent foetus: A report of two cases [PDF]

open access: yes, 2009
Molar pregnancy with a co-existent foetus will lead to preterm labour, severe preeclampsia or bleeding in most of the cases and may need urgent intervention.
Boustani, P.   +3 more
core  

Uterine natural killer cell heterogeneity: Lessons from mouse models [PDF]

open access: yes, 2020
Natural killer (NK) cells are the most abundant lymphocytes at the maternal-fetal interface. Epidemiological data implicate NK cells in human pregnancy outcomes.
Sojka, Dorothy K
core   +1 more source

Dysregulated placental microRNAs in Early and Late onset Preeclampsia [PDF]

open access: yes, 2018
Copyright © 2017. Published by Elsevier Ltd.INTRODUCTION: To determine the miRNA expression profile in placentas complicated by Preeclampsia (PE) and compare it to uncomplicated pregnancies.
Braoudaki, Maria   +8 more
core   +2 more sources

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