Results 141 to 150 of about 725,003 (400)
Advanced Science, EarlyView.This work found that early‐stage insulin sensitization but late‐stage insulin resistance in prenatal caffeine exposure (PCE)‐ induced intrauterine growth restriction (IUGR) offspring may be related to the hepatic AGEs accumulation via intrauterine GR/miR‐1224 programming by glucocorticoids.
Yongguo Dai +5 more
wiley +1 more source
The effect of maternal iron deficiency on zinc and copper levels and on genes of zinc and copper metabolism during pregnancy in the rat [PDF]
, 2019 Fe deficiency is relatively common in pregnancy and has both short- and long-term consequences. However, little is known about the effect on the metabolism of other micronutrients.
Cottin, Sarah C. +5 more
core +4 more sources
Global Challenges, 2019 Due to the particular structure and functionality of the placenta, most current human placenta drug testing methods are limited to animal models, conventional cell testing, and cohort/controlled testing.
Rajeendra L. Pemathilaka +4 more
semanticscholar +1 more source
Advanced Science, EarlyView.Elevated levels of the plasticizer DEHP associate with earlier breast cancer diagnosis. DEHP enhances glutamine‐powered energy production via the transporter SLC6A14 and pushes mitochondria toward fusion, driving tumor initiation by boosting cancer stemness. Blocking SLC6A14 lowers stemness, slows tumors, and improves chemotherapy response.
Dai‐Wei Hu +15 more
wiley +1 more source
Upsala Journal of Medical Sciences, 2017 Objective: Women previously giving birth with cesarean section have an increased risk of postpartum hemorrhage (PPH) and retained placenta. The objective of this study was to determine if anterior placental location increased the risk of PPH and retained
Johanna Belachew +3 more
doaj +1 more source
Placental Structure in Preterm Birth Among HIV-Positive Versus HIV-Negative Women in Kenya. [PDF]
, 2019 BackgroundPreterm birth (PTB) is a major cause of infant morbidity and mortality in developing countries. Recent data suggest that in addition to Human Immunodeficiency Virus (HIV) infection, use of antiretroviral therapy (ART) increases the risk of PTB.
Cohen, Craig R +7 more
core
Morphology and physiology of rat placenta for toxicological evaluation
Journal of Toxicologic Pathology, 2018 The placenta plays a pivotal role in fetal growth, and placental dysfunction and injury are associated with embryo/fetal toxicity. Histological examination of the rat placenta for safety evaluation provides valuable clues to the mechanisms of this ...
S. Furukawa, Naho Tsuji, A. Sugiyama
semanticscholar +1 more source
Laeverin is Cell‐Surface Target for Liquid‐Phase Metastasizing Cancer Cells
Advanced Science, EarlyView.This study revealed that epithelial cancer cells in the floating phase induce the expression of laeverin (LVRN) that is a trophoblast‐specific and cell‐surface immunoregulatory factor and showed that anti‐LVRN ADC is a promising agent that can attack cancer cells in the metastatic liquid phase and block further distant metastasis.
Haruki Kasama +17 more
wiley +1 more source
Metabolomics application in maternal-fetal medicine [PDF]
, 2013 Metabolomics in maternal-fetal medicine is still an "embryonic" science. However, there is already an increasing interest in metabolome of normal and complicated pregnancies, and neonatal outcomes. Tissues used for metabolomics interrogations of pregnant
Atzori, L +4 more
core +4 more sources
PIEZO Force Sensing in Vascular Biology: An Explosion of New Knowledge, Concepts and Opportunity
Advanced Science, EarlyView.Knowledge of the remarkable mechanical force sensing and electrically transducing PIEZO1 and PIEZO2 channels is discussed across vascular biology and its cell types from the embryonic to adult stages in health, disease and old age. How the channels work, relate to other factors and signal for tissue responses to mechanical forces is debated.
David J Beech
wiley +1 more source