Results 11 to 20 of about 732,852 (398)

Epidemiology of placenta previa accreta: a systematic review and meta-analysis

BMJ Open, 2019
Objective To estimate the prevalence and incidence of placenta previa complicated by placenta accreta spectrum (PAS) and to examine the different criteria being used for the diagnosis.Design Systematic review and meta-analysis.Data sources PubMed, Google
Catey Bunce, Eric Jauniaux, Lene Grønbeck, Jens Langhoff-Roos, Sally L Collins   +4 more
doaj   +2 more sources

Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy.

Journal of the American Chemical Society, 2023
Ionizable lipid nanoparticles (LNPs) are the most clinically advanced nonviral platform for mRNA delivery. While they have been explored for applications including vaccines and gene editing, LNPs have not been investigated for placental insufficiency ...
K. Swingle, Hannah C. Safford, Hannah C. Geisler, Alex G. Hamilton, Ajay S Thatte, Margaret M. Billingsley, Ryann A. Joseph, Kaitlin Mrksich, Marshall S. Padilla, Aditi A Ghalsasi, M. Alameh, D. Weissman, M. J. Mitchell   +12 more
semanticscholar   +1 more source

The Pivotal Role of the Placenta in Normal and Pathological Pregnancies: A Focus on Preeclampsia, Fetal Growth Restriction, and Maternal Chronic Venous Disease

Cells, 2022
The placenta is a central structure in pregnancy and has pleiotropic functions. This organ grows incredibly rapidly during this period, acting as a mastermind behind different fetal and maternal processes. The relevance of the placenta extends far beyond
M. Ortega, Ó. Fraile-Martínez, C. García-Montero, M. A. Sáez, M. Álvarez-Mon, Diego Torres-Carranza, M. Álvarez-Mon, J. Buján, N. García-Honduvilla, Coral Bravo, L. Guijarro, J. D. De León-Luis   +11 more
semanticscholar   +1 more source

SARS-CoV-2 infection of the placenta.

Journal of Clinical Investigation, 2020
BACKGROUND The effects of Covid-19 in pregnancy remain relatively unknown. We present a case of second trimester pregnancy with symptomatic Covid-19 complicated by severe preeclampsia and placental abruption.
H. Hosier, S. Farhadian, R. Morotti, U. Deshmukh, Alice Lu-Culligan, K. Campbell, Yuki Yasumoto, C. Vogels, A. Casanovas-Massana, P. Vijayakumar, B. Geng, C. Odio, John B. Fournier, A. Brito, J. Fauver, Feimei Liu, T. Alpert, R. Tal, Klara Szigeti-Buck, Sudhir Perincheri, C. Larsen, A. Gariepy, G. Aguilar, Kristen L. Fardelmann, M. Harigopal, H. Taylor, C. Pettker, A. Wyllie, C. D. Cruz, A. Ring, N. Grubaugh, A. Ko, T. Horvath, A. Iwasaki, U. Reddy, H. Lipkind   +35 more
semanticscholar   +1 more source

The Hypoxic Placenta [PDF]

High Altitude Medicine & Biology, 2012
Hypoxia of the placenta is integral to complications of pregnancy, including preeclampsia, intrauterine growth restriction, and small-for-gestational age babies. Hypoxia in the placenta is associated with vascular remodeling, hypertension, metabolic changes, oxidative stress, mitochondrial dysfunction, and endoplasmic reticular stress.
Tissot van Patot, Martha C, Ebensperger, German, Gassmann, Max, Llanos, Aníbal J   +3 more
openaire   +3 more sources

Retained placenta after vaginal delivery: risk factors and management

International Journal of Women's Health, 2019
Nicola C Perlman, Daniela A Carusi Department of Obstetrics and Gynecology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USACorrespondence: Daniela A CarusiDepartment of Obstetrics and Gynecology, Brigham and Women’s ...
Perlman NC, Carusi DA
doaj   +2 more sources

Telomeric NAP1L4 and OSBPL5 of the KCNQ1 cluster, and the DECORIN gene are not imprinted in human trophoblast stem cells [PDF]

, 2010
Background: Genomic imprinting of the largest known cluster, the Kcnq1/KCNQ1 domain on mChr7/hChr11, displays significant differences between mouse and man.
Frost, J.M., Moore, G.E., Moore, H.D., Udayashankar, R.   +3 more
core   +9 more sources

Protocol to derive human trophoblast stem cells directly from primed pluripotent stem cells

STAR Protocols, 2022
Summary: Human trophoblast stem cells (hTSCs) are useful for studying human placenta development and diseases, but primed human pluripotent stem cells (hPSCs) routinely cultured in most laboratories do not support hTSC derivation.
Yanxing Wei, Lu Xiao, Lishi Ma, Zhijian Wang, Liping Huang, Huiying Li, Guangjin Pan, Stephen J. Lye, Yongli Shan   +8 more
doaj   +1 more source

First report of caprine abortions due to Chlamydia abortus in Argentina. [PDF]

, 2019
Infectious abortions of goats in Argentina are mainly associated with brucellosis and toxoplasmosis. In this paper, we describe an abortion outbreak in goats caused by Chlamydia abortus. Seventy out of 400 goats aborted.
Alvarado Pinedo, María F, Di Paolo, Leandro A, Fernández, Gerardo, Origlia, Javier, Travería, Gabriel E, Uzal, Francisco A   +5 more
core   +3 more sources

The placenta‐brain‐axis

Journal of Neuroscience Research, 2020
All mammalian species depend on the placenta, a transient organ, for exchange of gases, nutrients, and waste between the mother and conceptus. Besides serving as a conduit for such exchanges, the placenta produces hormones and other factors that ...
C. Rosenfeld
semanticscholar   +1 more source