Results 251 to 260 of about 854,609 (354)

Circulating hsa‐miR‐29c‐3p and VEGF‐A levels predict the response to FOLFIRI plus aflibercept in elderly metastatic colorectal cancer patients

European Journal of Clinical Investigation, EarlyView.
Metastatic colorectal cancer (mCRC) patients who progress on oxaliplatin‐based chemotherapy benefit from second‐line treatment with FOLFIRI plus aflibercept. However, the absence of validated biomarkers for antiangiogenic therapies remains a challenge. Circulating levels of VEGF‐A and 13 miRNAs were analysed in 154 elderly mCRC patients.
Marta Toledano‐Fonseca, María Teresa Cano‐Osuna, Elena Élez, Javier Soto‐Alsar, David Páez, Ana Fernández‐Montes, Begoña Graña, Antonieta Salud, Alfonso Yubero, Ismael Macías, Guillermo Quintero, Carlos López‐López, Teresa Fernández‐Rodríguez, María Victoria García‐Ortiz, Javier Sastre, Pilar García‐Alfonso, Antonio Rodríguez‐Ariza, Enrique Aranda, on behalf of the Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)   +18 more
wiley   +1 more source

Folate transfer across the placenta during late pregnancy in women with epilepsy: A cross‐sectional, two‐center study

Epilepsia, EarlyView.
Abstract Objective In women with epilepsy who are treated with antiseizure medications (ASMs), folate concentrations in maternal serum may not be a good indicator of fetal folate supply, because ASMs can interfere with folate handling by the placenta. We aimed to assess the transplacental folate transfer at birth in persons with epilepsy in comparison ...
Erez Berman, Gali Pariente, Natalia Erenburg, Roa’a Hamed, Cecilie Johannessen Landmark, Michal Kovo, Sara Eyal   +6 more
wiley   +1 more source

Examining the association between placental malperfusion assessed by histopathological examination and child and adolescent neurodevelopment: a systematic review

Journal of Child Psychology and Psychiatry, EarlyView.
Background Placental malperfusion, categorised into maternal vascular malperfusion (MVM) and foetal vascular malperfusion (FVM), is a main placental pathology known to affect placental functioning and offspring outcomes. The aim of this review is to evaluate the association between exposure to placental malperfusion and offspring neurodevelopment from ...
Noha Ibrahim, Sydni A. Weissgold, Lucy Brink, Ibtihal Mahgoub, Ben Carter, Vaheshta Sethna, Hein Odendaal   +6 more
wiley   +1 more source

Impact of excessive hypercholesterolemia in pregnancy on the placentas of the male and female offspring. [PDF]

Sci Rep
de Oliveira AA, Stokes A, Quon A, Graton ME, Spaans F, Cooke CM, Davidge ST.   +6 more
europepmc   +1 more source

The role of 67 kDa laminin receptor in G-CSF-induced hematopoietic stem cell mobilization [PDF]

, 2007
Visconte, Valeria
core   +1 more source

Circulating cell‐free mitochondrial DNA in diabetes mellitus: Current insights and unexplored frontiers

Journal of Diabetes Investigation, EarlyView.
Circulating cell‐free mitochondrial DNA may play a crucial role in the pathophysiology of diabetes and its complications, making it a potential diagnostic, prognostic, and therapeutic target. Abstract The role and significance of circulating cell‐free mitochondrial DNA (ccf‐mtDNA)—small fragments of mitochondrial DNA present in plasma—are becoming ...
Mohammadreza Akbari, Fatemeh Masjedi, Mohammad Nekooeian, Mahintaj Dara, Jamshid Roozbeh   +4 more
wiley   +1 more source

Microchimerism and pregnancy complications with placental dysfunction. [PDF]

Semin Immunopathol
Jacobsen DP, Fjeldstad HE, Olsen MB, Sugulle M, Staff AC.   +4 more
europepmc   +1 more source

Radionuclide and angiographic studies of placental circulation in man and rhesus monkey

, 1975
M Panigel, A. Everette James, M. H. Siegel, Martin W. Donner   +3 more
openalex   +1 more source

Plastics in dermatology: A review and solutions

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This review explores the environmental and health impacts of plastics, particularly microplastics in dermatological products. It discusses the plastic life cycle, routes of exposure, health risks and provides science‐based recommendations to reduce plastic use in dermatology.
Eugene Tan, Susanne Saha, Dennis Niebel
wiley   +1 more source

The Molecular Pathology of Pre-Eclamptic Hypertension. [PDF]

Curr Issues Mol Biol
Carrell RW, Read RJ, Zhou A.
europepmc   +1 more source