Results 21 to 30 of about 78,143 (322)

Characterization of a human placental clearance system to regulate serotonin levels in the fetoplacental unit

Reproductive Biology and Endocrinology, 2023
Background Serotonin (5-HT) is a biogenic monoamine with diverse functions in multiple human organs and tissues. During pregnancy, tightly regulated levels of 5-HT in the fetoplacental unit are critical for proper placental functions, fetal development ...
Frantisek Staud, Xin Pan, Rona Karahoda, Xiaojing Dong, Petr Kastner, Hana Horackova, Veronika Vachalova, Udo R. Markert, Cilia Abad   +8 more
doaj   +1 more source

Loss of maternal annexin A5 increases the likelihood of placental platelet thrombosis and foetal loss [PDF]

, 2012
Antiphospholipid syndrome is associated with an increased risk of thrombosis and pregnancy loss. Annexin A5 (Anxa5) is a candidate autoantigen. It is not known, however, whether endogenous Anxa5 prevents foetal loss during normal pregnancy.
Brachvogel, Bent, Hasegawa, Yoshihisa, Kawaminami, Mitsumori, Kurusu, Shiro, Laoharatchatathanin, Titaree, Mizushina, Tomona, Nishimura, Yasuhiro, Poschl, Ernst, Rieanrakwong, Duangjai, Terashima, Ryota, Ueki, Hiroshi, Yonezawa, Tomohiro   +11 more
core   +1 more source

INCREASING THE NITRIC OXIDE BIOAVAILABILITY AND ADAPTATION OF MATERNAL-PLACENTAL-FETAL HEMODYNAMICS IN THE TREATMENT OF THE PLACENTAL INSUFFICIENCY

Медицинский вестник Юга России, 2013
Purpose: To reveal changes in maternal, placental and fetal circulation after the inhibitor phosphodiesterase-5 (Sildenafil citrate) use in the treatment of placental insufficiency.Materials and Methods: Based on a randomized double-blinded and placebo ...
V. S. Gimbut, T. L. Botasheva, V. V. Avrutskaya, N. V. Palieva   +3 more
doaj   +1 more source

Hyper-methylation of AVPR1A and PKCΒ gene associated with insensitivity to arginine vasopressin in human pre-eclamptic placental vasculatureResearch in context

EBioMedicine, 2019
Background: Pre-eclampsia is a leading cause of maternal mortality and morbidity. Although the exact mechanisms that cause pre-eclampsia remain unclear, it is undeniable that abnormal placental function and circulation are a center for initiation pre ...
Qinqin Gao, Huan Li, Hongmei Ding, Xiaorong Fan, Ting Xu, Jiaqi Tang, Yanping Liu, Xueyi Chen, Xiuwen Zhou, Jianying Tao, Zhice Xu   +10 more
doaj   +1 more source

Differential expression of microRNA-206 and its target genes in pre-eclampsia [PDF]

, 2015
Objectives: Pre-eclampsia is a multi-system disease that significantly contributes to maternal and fetal morbidity and mortality. In this study, we used a non-biased microarray approach to identify novel circulating miRNAs in maternal plasma that may be ...
Akehurst, Christine, Beattie, Wendy, Brown, Catriona E., Carty, David M., Delles, Christian, Forrest, Rachel, Freeman, Dilys J., McBride, Martin W., McClure, John D., Robinson, Scott W., Sharafetdinova, Liliia, Small, Heather, Work, Lorraine M.   +12 more
core   +1 more source

A review on development of placental transfusion in term and preterm infants

Frontiers in Pediatrics, 2022
In recent years, it has been verified that placental transfusion can replenish blood volume of neonates, improve organ perfusion in the early postnatal stage, and facilitate the transition from fetal circulation to adult circulation. Meanwhile, placental
Jiangyi Lu, Guang Yue, Qianying Wang, Xiaofeng Zhou, Rong Ju   +4 more
doaj   +1 more source

Biomarkers in acute coronary syndromes and their role in diabetic patients [PDF]

, 2005
Diabetic patients with acute coronary syndromes are at high risk for cardiovascular complications but risk stratification in these patients remains challenging.
Christopher Heeschen, Heeschen C, James SK, Khaliq A, Luttun A, Mak KH   +5 more
core   +1 more source

Inhibition of Trophoblast-Induced Spiral Artery Remodeling Reduces Placental Perfusion in Rat Pregnancy. [PDF]

, 2010
Rats harboring the human angiotensinogen and human renin genes develop preeclamptic features in pregnancy. The preeclamptic rats exhibit a deeper trophoblast invasion associated with a reduced resistance index by uterine Doppler.
Cartwright, JE, Davidge, ST, Dechend, R, Dudenhausen, JW, Geusens, N, Hering, L, Herse, F, Luft, FC, Morton, J, Muller, DN, Pijnenborg, R, Verhaegen, I, Verlohren, S   +12 more
core   +1 more source

Hemodynamic abnormalities of feto-placental complex in influenza virus infection

Zaporožskij Medicinskij Žurnal, 2017
The aim of the work was to carry out of ultrasound examination of a feto-placental complex in pregnant women who were infected with influenza or infected with influenza at the time of examination. Materials and Methods.
L. R. Nikogosyan, V. P. Mishchenko, I. V. Rudenko, V. K. Likhachov   +3 more
doaj   +1 more source

Hepcidin and iron homeostasis during pregnancy. [PDF]

, 2014
Hepcidin is the master regulator of systemic iron bioavailability in humans. This review examines primary research articles that assessed hepcidin during pregnancy and postpartum and report its relationship to maternal and infant iron status and birth ...
Cadwell, Brooke, Day, Jessica, Koenig, Mary Dawn, Nemeth, Elizabeta, Tussing-Humphreys, Lisa   +4 more
core   +1 more source