Results 101 to 110 of about 403,052 (287)
Recovering the lost gold of the developing world : bibliographic database [PDF]
, 1999 This report contains a library of 181 references, including abstracts, prepared for Project R 7120 "Recovering the lost gold of the developing world" funded by the UK' s Department for International Development (DFID) under the Knowledge and Research (
Evans, E.J., Mitchell, C.J.
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Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Fundamentos de la ética sexual
Estudios Eclesiásticos, 1975 La sexualidad y el sexo son un arma de doble filo: una experiencia que se puede vivir como alegría y gozo o puede conducir a la amargura, al fracaso y al dolor.
Eduardo López Azpitarte
doaj
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Journal of MMIJThis study investigates the mineral diversity in placer platinum-group minerals (placer PGM) purportedly collected from the Onnebetsu area in Shibetsu City, Hokkaido.
Toru OISHI, Daisuke NISHIO-HAMANE
doaj +1 more source
The effects of placer mining on the environment in Central Alaska [PDF]
, 1982 Within the Tolovana Mining District, as a result of placer mining, 800 acres of land have been disturbed (0.25% of the land area) and 4 million cubic yards of much have been transported down the Tolovana River through the subsiding Minto Flats. This has
Thomas, B, Wolff, E.N.
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Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Sizing Up: Strategies for Staffing Emerging Community Foundations [PDF]
, 2012 It is rare that a community foundation believes it has sufficient resources to create the positive impact it envisions for its community. For small community foundations, this frustration is often amplified.
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