Results 101 to 110 of about 318,051 (294)
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Studies of Peptide Antibiotics. XXVII. Synthesis of an Analog of Gramicidin S Containing a Glycine Residue in Place of a Proline [PDF]
Shuji Matsuura +2 more
openalex +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
La formación musical como pasión comunicativa = The musical education as communicative passion
The article is written in dissidence and disagreement with the symbolic universe of modernity (concerning the sciences, technology, experts, virtuosi and professionals). It tries to present based on the sociological imagination, discoursive resources and
Placer, Fernando González
doaj
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Endapan Emas Placer Di Daerah Wumbubangka Kecamatan Rarowatu Dan Rarowatu Utara, Kabupaten Bombana Sulawesi Tenggara [PDF]
Sapto Heru Yuwanto, Satria Heruroso
openalex +1 more source
How Many Events do You Need? Event-based Visual Place Recognition Using Sparse But Varying Pixels [PDF]
Tobias Fischer, Michael Milford
openalex +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source

