Results 101 to 110 of about 404,483 (304)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Learning to Lead: The Journey to Community Leadership for Emerging Community Foundations [PDF]
, 2012 The James Irvine Foundation launched its Community Foundations Initiative II in 2005. This six-year effort involved a $12 million investment to accelerate the growth and leadership of a set of small and young community foundations in rural areas of ...
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Insights into a long life without cancer: The case of the bowhead whale
Molecular Oncology, EarlyView.Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley +1 more source
Journal of MMIJThis study investigates the mineral diversity in placer platinum-group minerals (placer PGM) purportedly collected from the Onnebetsu area in Shibetsu City, Hokkaido.
Toru OISHI, Daisuke NISHIO-HAMANE
doaj +1 more source
Health Status of the Uninsured: Opportunities for Improvement [PDF]
, 2004 Provides estimates of the geographic variations in the rates of self-reported fair or poor health status, asthma, and hypertension among uninsured children and adults in ...
Carolyn A. Mendez-Luck +4 more
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Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Onanismo, el funesto placer solitario [PDF]
, 2009 La palabra “onanismo” proviene de un error en la percepción del pecado de codicia de Onán, el cual fue tomado como pecado carnal. En la antigüedad, el placer fue visto como un signo de salud física y moral hasta que la medicina griega consideró que el ...
Iglesias Benavides, José Luis
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FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source