Results 21 to 30 of about 28,471 (312)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Application of the 190Pt-186Os isotope decay system to dating platinum-group minerals [PDF]

open access: yes, 2010
Constraining the formation age of platinum-group minerals (PGM) in placer deposits has traditionally been very challenging. The 190Pt-186Os decay system, measured by laser ablation multi-collector ICPMS (LA-MC-ICPMS), has been demonstrated as a useful ...
Coggon, Judith Ann, COGGON, JUDITH,ANN
core  

¿Por qué un hedonista habría de elegir la muerte? Los cirenaicos y la actitud de Sócrates frente a la acusación judicial

open access: yesPensamiento. Revista de Investigación e Información Filosófica, 2021
El fenómeno del diálogo socrático describe la adopción por parte de varios integrantes del grupo de la figura de Sócrates, a quien atribuyen sus propias ideas, dando lugar a perfiles alejados de las variantes más conocidas, como las de Platón o Jenofonte.
Claudia Mársico
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

El placer de aprender [PDF]

open access: yes, 2018
Estudios recientes en neurociencia explican las bases biológicas de por qué es importante asociar las experiencias de aprendizaje con el placer, ya que aprender es placentero por naturaleza.
Bueno i Torrens, David, 1965-   +1 more
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Vipava fault (Slovenia)

open access: yesGeologija, 2008
During mapping of the already accomplished Razdrto – Senožeče section of motorway and geologic surveying of construction operations of the trunk road between Razdrto and Vipava in northwestern part of External Dinarides on the southwestern slope of Mt ...
Ladislav Placer
doaj  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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