Results 41 to 50 of about 21,152 (308)

Minerals in Afghanistan : the potential for gold [PDF]

open access: yes, 2006
Gold has been worked in Afghanistan for centuries from many areas including Takhar province in the north and from Ghazni, Zabul, and Kandahar provinces in the south-west of the country.
Benham, Antony John, Coats, Stan
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

A four stage evolution of the White Channel gravel: Implications for stratigraphy and palaeoclimates [PDF]

open access: yes, 2014
Although the White Channel gravel (WCG) of the Klondike district, Yukon, contains gold placers which have been exploited for over a century, few sedimentological studies have been undertaken.
Chapman, Robert   +3 more
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Sixth annual conference on alaskan placer mining [PDF]

open access: yes, 1984
An abridged format of papers, presentations and addresses given during the 1984 conference held on March 28-29, 1984, compiled and edited by Daniel E. Walsh and M.
Walsh, D.E., Wray, Susan
core  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Assessment of the prospects of the Dzhagdy-Selemdzinskaya gold-bearing metallogenic zone of Priamurskaya province

open access: yesИзвестия высших учебных заведений: Геология и разведка, 2015
Dzhagdy-Selemdzinskaya metallogemc zone is shown to be the one of the most productive gold-bearing zones in Priamurskaya province. The placer and ore deposits mined in the area are estimated to be about 350 t of gold, including 293,811 of placer and 57 ...
V. A. Stepanov, A. V. Melnikov
doaj   +2 more sources

Mineralogy and Provenance of Iron Sand Deposits from Cipatujah and Cikalong, Tasikmalaya, West Java, Indonesia

open access: yesIraqi Geological Journal, 2023
Provenance, paleoweathering, and tectonic environment were studied on the iron sand samples taken from Cipatujah and Cikalong areas in Tasikmalaya, West Java, Indonesia using their mineralogical and geochemical data.
Hariro Zahra   +5 more
doaj   +1 more source

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