Results 61 to 70 of about 21,152 (308)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Applicability of siberian placer mining technology to Alaska [PDF]

, 1991
The result of Perestroyka and Glasnost has been an awakening of potential for cooperation between East and West. Nowhere has that been better demonstrated than between Alaska and Magadan Province, USSR. This report summarizes a one year effort financed
Barker, J.C., MacDonald, Rocky, Skudrzyk, F.J., Walsh, D.E.   +3 more
core  

The application of deep eutectic solvent ionic liquids for environmentally-friendly dissolution and recovery of precious metals [PDF]

, 2016
publisher: Elsevier articletitle: The application of deep eutectic solvent ionic liquids for environmentally-friendly dissolution and recovery of precious metals journaltitle: Minerals Engineering articlelink: http://dx.doi.org/10.1016/j.mineng.2015.09 ...
Abbott, Abbott, Abbott, Abbott, Abbott, Ahmed Z.M. Al-Bassam, Andrew P. Abbott, Chapman, Christopher J. Stanley, Curtis, Daniel J. Smith, David A. Holwell, Dominy, Dong, Gawen R.T. Jenkin, Groen, Hill, Luczak, Robert C. Harris, Robert J. Chapman, Schouwstra, Smith, Spry, Vaughan, Wadsworth, Whitehead, Whitehead, Whitehead, Woodhouse, Zhang   +29 more
core   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Justification of the optimal width of a front bank

Горные науки и технологии
Reducing the cost of finished products by using the most economically advantageous processes and techniques for the extraction and beneficiation of minerals is one of the most pressing tasks in mining industry.
B. L. Talgamer, I. A. Meshkov, N. V. Murzin, Yu. G. Roslavtseva   +3 more
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Application of portable delayed neutron activation analysis equipment in the evaluation of gold deposits [PDF]

, 1980
The attributes of a gold analysis system which could act as a panacea for the needs of the explorationist and the miner alike would include: i) The capability of being used as a qualitative as well as a quantitative tool yielding accurate results in ...
Sims, J.M.
core  

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

THE FIRST DATA ON THE U-PB AGE (TIMS AND LA-ICP-MS) OF RUTILE FROM THE ICHETJU POLYMINERAL OCCURRENCE, THE MIDDLE TIMAN

Записки Горного института, 2018
A study on the U-Pb age of rutile from the Ichetju polymineral occurrence has been done for the first time by LA-ICP-MS and TIMS methods. It was established that rutile originates from various sources with different ages (presumably, ca. 1000, 1660, 1860
S. G. Skublov, A. O. Krasotkina, A. B. Makeev, N. G. Rizvanova, E. Koiman   +4 more
doaj   +1 more source