Results 61 to 70 of about 305,652 (296)

Geomorphometric analysis of Zimbabwe’ digital elevation model and issues of exogenic metallogeny

open access: yesИзвестия высших учебных заведений: Геология и разведка
Background. The raw material base of the Republic of Zimbabwe covers numerous endogenic deposits of chromium, nickel, copper, platinum, gold, diamonds, and other minerals. Exogenic deposits are of less occurrence.
P. A. Ignatov   +3 more
doaj   +1 more source

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

open access: yesFEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman   +3 more
wiley   +1 more source

PREREQUISITES FOR THE FORMATION OF GOLD SPREADS ON THE UKRAINIAN SHIELD AND ON ITS SOUTHERN FRAMING

open access: yesГеологія і корисні копалини Світового океану, 2023
The presence of numerous native gold deposits of the Ukrainian Crystalline Shield (UCS), as well as the spread of placer gold manifestations, determines the high probability of the formation of precious metal placers with industrial parameters here.
I.E. Lomakin   +2 more
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

About micro- and nanoscale gold in the veil of gold-bearing territories (on the example of a mineralization site in the basin of the river Adamikha, Amur region)

open access: yesGeoresursy
The article identifies the problem of the need to take into account micro- (1 mm to 0.12 microns) and nanoscale (<0.12 microns) gold in placers and weathering crusts in order to increase the objectivity of their and eroded ore objects potential ...
I. V. Kuznetsova, A. I. Dementienko
doaj   +1 more source

Hydraulic borehole mining method possible application at Middle Larba alluvial gold field

open access: yesE3S Web of Conferences, 2018
Gold on placer deposits is mainly extracted in two ways: open and underground. But the open method of mining has a great negative impact on the environment, and the mine method is characterized by high labor intensity, capital and operating costs.
Rochev Vikror
doaj   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Fabrication of Patient's Elastic Placer

open access: yesJournal of Indian Orthodontic Society, 2014
Successful treatment outcome go hand in hand with the appro­ priate use of elastics. Many patients find difficult to engage to and remove the elastics from the intraoral attachments/hooks. This task is often frustrating and in turn lead to poor compliance and inefficient settling.
N Siddhartha   +7 more
openaire   +2 more sources

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

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