Results 171 to 180 of about 422,485 (391)

Yersinia pestis--etiologic agent of plague

open access: yesClinical Microbiology Reviews, 1997
R. Perry, Jacqueline D. Fetherston
semanticscholar   +1 more source

A Porcine Monoclonal Antibody Targeting a Conserved GP4 Epitope Protects against In Vivo Infection via the Induction of Broad‐Spectrum PRRSV Neutralization

open access: yesAdvanced Science, EarlyView.
This study developed mAb‐5F2, a monoclonal antibody targeting conserved GP4 residues (Q48/I50), which blocks the GP4‐CD163 interaction, resulting in a 78–85% reduction in viral entry. Porcineized 5F2‐pFc prevented mortality in infected piglets, reduced pulmonary viral loads, and minimized lesions. This broad‐spectrum antibody platform overcomes vaccine
Xu Chen   +12 more
wiley   +1 more source

EVALUATION OF VIBRIO CHOLERAE 569B INABA PROTECTIVE ANTIGENES, DERIVED ON INDUSTRIAL AND DEVELOPED BIOREACTORS AS WELL AS BY IMPROVED TECHNOLOGY

open access: yesActa Biomedica Scientifica, 2012
We evaluated immunochemical, physical and biochemical properties of Vibrio cholerae 569B INABA protective antigenes, derived on industrial and own-developed bioreactors as well as by technology of its concentration by tangential ultrafiltration.
A. K. Nikiforov   +9 more
doaj  

The Power of Plagues

open access: yesEmerging Infectious Diseases, 2006
The purpose of this book is to make the science of epidemic diseases accessible and understandable; to guide the general reader through the maze of contagious diseases, their past importance, the means by which we came to understand them, and how they may affect our future.
openaire   +3 more sources

MoMtg1 Acts as a Novel Transcriptional Repressor of MoSwi6 During Appressorium‐Mediated Penetration in the Rice Blast Fungus

open access: yesAdvanced Science, EarlyView.
Appressoria are specialized penetration structures for many plant pathogenic fungi, demanding precise cell cycle control. This study unveils MoMtg1 as a transcriptional repressor of MoSwi6, orchestrating MoCYC1 expression during turgor‐driven cell cycle progression to enable appressorium‐mediated penetration. Moreover, a small‐molecule inhibitor ZS1619
Xingyu Wang   +11 more
wiley   +1 more source

Enhancer Reprogramming Reveals the Tumorigenic Role of PTPRZ1 in Lung Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Lung squamous cell cancer (LUSC) is deadly due to lack of good treatments. Here, multiomics techniques are applied to LUSC tumors and find thousands of cancer‐specific enhancers controlling key genes. Interestingly, the gene PTPRZ1 is identified as a critical oncogene driven by the LUSC‐acquired enhancers. PTPRZ1 is activated by MDK, fueling cancer via
Yong‐Qiang Ning   +11 more
wiley   +1 more source

RiboMicrobe: An Integrated Translatome Atlas for Microorganism

open access: yesAdvanced Science, EarlyView.
RiboMicrobe is a comprehensive database for Ribo‐seq data from prokaryotes, featuring 891 Ribo‐seq, 369 RNA‐seq, and 62 proteome datasets from 38 species. The database not only provides various data visualization results but also includes two sORF prediction models and a suit of bioinformatics tools for comparative analysis, facilitating easy access ...
Yingshun Zhou   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy