Results 71 to 80 of about 66,539 (264)

Peculiarities of Epidemiological Situation on the West Nile Fever in 2012 in the Territory of the Russian Federation

Проблемы особо опасных инфекций, 2013
During the epidemic season of 2012 453 cases of West Nile fever (WNF) were registered in the territory of the 21 constituent entities of the Russian Federation. Epidemic process is spreading itself towards the northern regions of Russia.
E. V. Putintseva, V. A. Antonov, D. V. Viktorov, V. P. Smelyansky, K. V. Zhukov, V. V. Manankov, N. I. Pogasy, G. A. Tkachenko, I. M. Shpak, E. A. Snatenkov   +9 more
doaj   +1 more source

POU2F1 Promotes Chemoresistance in Colorectal Cancer Cells via Attenuates the MDR2 Degradation Mediated by PPP1R11 Lactylation

Advanced Science, EarlyView.
Schematic diagram of our study showing that highly expressed POU2F1 in colorectal cancer (CRC) can directly accelerate the cytosolic lactate export to decrease PPP1R11 lactylation at K59, thereby attenuating the E3 ligase enzyme activity and protein stability of PPP1R11, which inhibits the ubiquitination of MDR2 at K413 and K538 but increases the ...
Longzheng Xia, Jinguan Lin, Xianjie Jiang, Linda Oyang, Shiming Tan, Zongyao Ren, Qiu Peng, Qianjin Liao, Yujuan Zhou   +8 more
wiley   +1 more source

Several Cytokine Profile Parameters in West Nile Fever Patients

Проблемы особо опасных инфекций, 2011
Presented are the results of cytokines' (IL-1, IL-2, IFN-γ, and TNF-α, IL-10) level detection in blood sera of West Nile fever patients in the territory of Volgograd Region during the summer outbreak in 2010. Marked is a significant increase in IL-1, IFN-
S. I. Zhukova, V. V. Alekseev, A. V. Lipnitsky, A. A. Zankovich, I. V. Avrorova, V. A. Antonov, V. P. Smelyansky, G. A. Tkachenko, E. V. Putintseva, O. V. Zinchenko   +9 more
doaj   +1 more source

Development‐based In Vivo Bioreactor Strategy for Challenging Senescent Bone Reconstruction

Advanced Science, EarlyView.
We present a development‐based in vivo bioreactor strategy to generate rejuvenated bone grafts (vBR‐Bone) within aged hosts. By enclosing vBR‐Bone fragments within an asymmetric biomimetic periosteum, segmental femoral defects in aged mice were successfully repaired within 6 weeks. Mechanistically, the multifactors of vBR‐Bone reconstitute a remodeling
Wenchao Zhang, Kai Dai, Tong Shen, Zehua Gao, Fengying Yan, Yuke Feng, Xuanlin Wang, Shaozhen Zhang, Jing Wang, Changsheng Liu   +9 more
wiley   +1 more source

DIAGNOSTIC POTENTIAL OF THE ERYTHROCYTIC IMMUNOGLOBULIN DIAGNOSTICUM FOR INDICATION AND IDENTIFICATION OF THE CAUSATIVE AGENTS OF PARTICULARLY DANGEROUS (DEEP) MYCOSES

Проблемы особо опасных инфекций, 2017
Objective of the study was to assess analytical and diagnostic sensitivity and specificity of the “Reagent kit. Erythrocytic coccidioidomycosal and histoplasmosal immunoglobulin dry diagnosticum”, designed for identification of causative agents of ...
I. V. Novitskaya, E. V. Prokhvatilova, A. V. Toporkov, D. V. Viktorov, M. Ya. Kulakov, E. V. Savina, V. G. Pushkar’, L. I. Belitskaya, N. A. Osina, Zh. A. Kas’yan, I. V. Shul’gina, O. A. Lobovikova   +11 more
doaj   +1 more source

Dual‐Physical‐Field Nanocatalysis: Injectable Hydrogel Enables Piezo‐Photothermal Synergy for Breast Cancer Therapy

Advanced Science, EarlyView.
ABSTRACT Piezocatalytic therapy (PCT) harnesses mechanical energy to generate tumor‐lethal reactive oxygen species (ROS), but its efficacy is limited by rapid electron‐hole recombination and poor intratumoral retention. To overcome these limitations, we engineered heterostructured BiOCl@CuO nanosheets embedded in an injectable, conductive ...
Can Tian, Shihan Xiao, Xuan Chen, Danni Zhang, Zizhen Liu, Jing Wang, Ning Xie, Wei Li   +7 more
wiley   +1 more source

Hierarchical Reconfigurable Metasurface Based on Scenario‐Guided Functional Modules and Programmable Core

Advanced Science, EarlyView.
This paper proposes a hierarchical reconfigurable metasurface architecture (HRMA) to achieve comprehensive electromagnetic parameter modulation and on‐demand polymorphic function switching. The reconfigurable metasurface is divided into a programmable core (PC) and scenario‐guided functional modules (FMs), exhibiting significant flexibility and ...
Lihao Zhu, Jiaqi Han, Zhe Zheng, Qiang Feng, Dexiao Xia, Xiangjin Ma, Yajie Mu, Guoliang Luo, Rui Li, Haixia Liu, Hao Xue, Long Li   +11 more
wiley   +1 more source

Mastering of Technology of Production of Brucellosis Diagnostic Bacteriophages

Проблемы особо опасных инфекций, 2009
Presented are technologies of production of brucellosis diagnostic bacteriophages developed on the basis of determination of optimal conditions of the phages reproduction. Stability of the finished product was evaluated using Shuhard control charts.
L. V. Lyapustina, P. A. Omelyanchuk, G. I. Lyamkin, S. V. Vilinskaya, S. I. Golovneva, O. I. Kogotkova, D. A. Budyka, D. V. Rusanova, A. N. Kulichenko   +8 more
doaj   +1 more source

Toward Flexible Printed Electronics: A Spider‐Silk‐Inspired, Strong and Tough Thermoplastic Polyamide Elastomer

Advanced Science, EarlyView.
Inspired by spider silk, a bio‐inspired polyamide elastomer with a dynamic physical cross‐linking network is developed. Mimicking the rigid β‐sheet crystals and sacrificial hydrogen bonds of silk, the material achieves an exceptional balance of strength and toughness.
Bo Yang, Liyue Zhang, Mengjing Yang, Hangzhi Guo, Zhibo Lin, Xinyu Qi, Wenjun Li, Haiyan Yan, Meng Li, Yanhui Chen, Weixing Chen, Zhenguo Liu, Wei Huang   +12 more
wiley   +1 more source

Experimental Study on Chemotherapy of Acute Glanders

Антибиотики и Химиотерапия, 2020
Glanders is a zoonotic infection inducing acute forms of the disease (pneumonia, sepsis) in humans and animals under certain conditions, which even with the use of modern chemotherapy have unfavourable prognosis.
V. I. Ilyukhin, K. A. Rotov, T. V. Senina, E. A. Snatenkov, S. N. Tikhonov, N. G. Plekhanova, A. S. Kulikova, E. V. Shubnikova, E. V. Korol, M. O. Nekhezina   +9 more
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