Results 21 to 30 of about 49,963 (311)

A self-amplifying RNA vaccine provides protection in a murine model of bubonic plague

Frontiers in Microbiology, 2023
Mice were immunized with a combination of self-amplifying (sa) RNA constructs for the F1 and V antigens of Yersinia pestis at a dose level of 1 μg or 5 μg or with the respective protein sub-units as a reference vaccine.
Robin John Shattock, Voahangy Andrianaivoarimanana, Paul F. McKay, Lovasoa Nomena Randriantseheno, Valarmathy Murugaiah, K. Samnuan, Paul Rogers, John S. Tregoning, Minoarisoa Rajerison, Kristoffer M. Moore, Thomas Robert Laws, E. Diane Williamson   +11 more
doaj   +1 more source

The Effect of Seasonal Weather Variation on the Dynamics of the Plague Disease

International Journal of Mathematics and Mathematical Sciences, 2017
Plague is a historic disease which is also known to be the most devastating disease that ever occurred in human history, caused by gram-negative bacteria known as Yersinia pestis.
Rigobert C. Ngeleja, Livingstone S. Luboobi, Yaw Nkansah-Gyekye   +2 more
doaj   +1 more source

Modeling the Justinianic Plague: Comparing hypothesized transmission routes.

PLoS ONE, 2020
The Justinianic Plague, the first part of the earliest of the three plague pandemics, has minimal historical documentation. Based on the limited primary sources, historians have argued both for and against the "maximalist narrative" of plague, i.e.
Lauren A White, Lee Mordechai
doaj   +1 more source

Role of the Yersinia pestis yersiniabactin iron acquisition system in the incidence of flea-borne plague. [PDF]

PLoS ONE, 2010
Plague is a flea-borne zoonosis caused by the bacterium Yersinia pestis. Y. pestis mutants lacking the yersiniabactin (Ybt) siderophore-based iron transport system are avirulent when inoculated intradermally but fully virulent when inoculated ...
Florent Sebbane, Clayton Jarrett, Donald Gardner, Daniel Long, B Joseph Hinnebusch   +4 more
doaj   +1 more source

Multiple Brucella melitensis lineages are driving the human brucellosis epidemic in Shaanxi Province, China: evidence from whole genome sequencing-based analysis

Frontiers in Cellular and Infection Microbiology
IntroductionHuman brucellosis is a severe public concern in Shaanxi Province, China, and investigating the epidemiological relationship and transmission pattern of B.
Cuihong An, Shoumin Nie, Boyan Luo, Dijia Zhou, Wenjing Wang, Yangxin Sun, Suoping Fan, Dongli Liu, Zhenjun Li, Zhiguo Liu, Wenhui Chang   +10 more
doaj   +1 more source

Performance of plague rapid diagnostic test compared to bacteriology: a retrospective analysis of the data collected in Madagascar

BMC Infectious Diseases, 2020
Background Plague is a highly fatal disease caused by Yersinia pestis. Late diagnosis hampers disease outcome and effectiveness of control measures, induces death and disease spread.
Minoarisoa Rajerison, Marie Melocco, Voahangy Andrianaivoarimanana, Soloandry Rahajandraibe, Feno Rakotoarimanana, André Spiegel, Maherisoa Ratsitorahina, Laurence Baril   +7 more
doaj   +1 more source

Plague Markings: Doors and Disease

Cultural History, 2023
Throughout history marking the home has often been used to convey urgent information about the ‘health’ of its inhabitants. These strategies frequently target the door or entrance to the household, as it presents a porous boundary between public and private spheres.
openaire   +2 more sources

Establishing the "One Health" concept within natural foci of plague on the Qinghai-Xizang Plateau

Zhongguo gonggong weisheng
This study, based on the natural foci of plague on the Qinghai-Xizang Plateau, explores the intricate interactions between humans, animals, and the environment.
Shun’an SHI, Haoming XIONG, Wenlong WANG, Xiaodong SU, Yongshun WANG, Peng CHEN, Jiancheng QI, Ke JIANG, Shoubiao XU, Long MA, Shengjun CAI, Guoqiang AN   +11 more
doaj   +1 more source

Plague circulation in small mammals elevates extinction risk for the endangered Peñasco least chipmunk

Global Ecology and Conservation, 2022
Wildlife diseases are a major concern for species survival around the world. Vector-borne diseases, in particular, are problematic for both humans and wildlife.
Amanda R. Goldberg, David A. Eads, Dean E. Biggins   +2 more
doaj   +1 more source

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

Advanced Functional Materials, EarlyView.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras, Imelda Raczkiewicz, Peggy Bouquet, Jean‐Philippe Dacquin, Jeremy Dhainaut, Anne Goffard, Christophe Volkringer   +6 more
wiley   +1 more source