Results 41 to 50 of about 9,260,529 (325)

Spatial analysis and identification of high risk plague regions in Pakistan based on associated rodent species distribution

Journal of Infection in Developing Countries, 2016
Plague, caused by Yersinia pestitis, is an infectious bacterial disease that has a high fatality rate if untreated. Rodents are plague reservoirs and play an important role in disease spread.
Madiha Shabbir, Maha Aleem, Sundus Javed, David M Wagner, Paul S Keim, Syed Ali Musstjab Akbar Shah Eqani, Habib Bokhari   +6 more
doaj   +1 more source

Human plague system associated with rodent diversity and other environmental factors [PDF]

Royal Society Open Science, 2019
Plague remains a threat to public health and is considered as a re-emerging infectious disease today. Rodents play an important role as major hosts in plague persistence and driving plague outbreaks in natural foci; however, few studies have tested the ...
Zhe Sun, Lei Xu, Boris V. Schmid, Katharine R. Dean, Zhibin Zhang, Yan Xie, Xiye Fang, Shuchun Wang, Qiyong Liu, Baolei Lyu, Xinru Wan, Jianguo Xu, Nils Chr. Stenseth, Bing Xu   +13 more
doaj   +1 more source

Role of the Yersinia pestis yersiniabactin iron acquisition system in the incidence of flea-borne plague. [PDF]

PLoS ONE, 2010
Plague is a flea-borne zoonosis caused by the bacterium Yersinia pestis. Y. pestis mutants lacking the yersiniabactin (Ybt) siderophore-based iron transport system are avirulent when inoculated intradermally but fully virulent when inoculated ...
Florent Sebbane, Clayton Jarrett, Donald Gardner, Daniel Long, B Joseph Hinnebusch   +4 more
doaj   +1 more source

Modeling the Justinianic Plague: Comparing hypothesized transmission routes.

PLoS ONE, 2020
The Justinianic Plague, the first part of the earliest of the three plague pandemics, has minimal historical documentation. Based on the limited primary sources, historians have argued both for and against the "maximalist narrative" of plague, i.e.
Lauren A White, Lee Mordechai
doaj   +1 more source

Yersinia pestis and Plague: some knowns and unknowns.

Zoonoses, 2023
Since its first identification in 1894 during the third pandemic in Hong Kong, there has been significant progress of understanding the lifestyle of Yersinia pestis, the pathogen that is responsible for plague.
Ruifu Yang, S. Atkinson, Ziqi Chen, Yujun Cui, Z. Du, Yanping Han, F. Sebbane, Philip Slavin, Yajun Song, Yanfeng Yan, Yarong Wu, Lei Xu, Chutian Zhang, Yun Zhang, B. J. Hinnebusch, N. Stenseth, V. Motin   +16 more
semanticscholar   +1 more source

Bacterial profiling of White Plague Disease across corals and oceans indicates a conserved and distinct disease microbiome

Molecular Ecology, 2014
Coral diseases are characterized by microbial community shifts in coral mucus and tissue, but causes and consequences of these changes are vaguely understood due to the complexity and dynamics of coral‐associated bacteria.
Cornelia M. Roder, Chatchanit Arif, C. Daniels, E. Weil, C. Voolstra   +4 more
semanticscholar   +1 more source

mRNA vaccines in disease prevention and treatment

Signal Transduction and Targeted Therapy, 2023
mRNA vaccines have emerged as highly effective strategies in the prophylaxis and treatment of diseases, thanks largely although not totally to their extraordinary performance in recent years against the worldwide plague COVID-19.
Gang Zhang, Tianyu Tang, Yinfeng Chen, Xing Huang, Tingbo Liang   +4 more
semanticscholar   +1 more source

Performance of plague rapid diagnostic test compared to bacteriology: a retrospective analysis of the data collected in Madagascar

BMC Infectious Diseases, 2020
Background Plague is a highly fatal disease caused by Yersinia pestis. Late diagnosis hampers disease outcome and effectiveness of control measures, induces death and disease spread.
Minoarisoa Rajerison, Marie Melocco, Voahangy Andrianaivoarimanana, Soloandry Rahajandraibe, Feno Rakotoarimanana, André Spiegel, Maherisoa Ratsitorahina, Laurence Baril   +7 more
doaj   +1 more source

A self-amplifying RNA vaccine provides protection in a murine model of bubonic plague

Frontiers in Microbiology, 2023
Mice were immunized with a combination of self-amplifying (sa) RNA constructs for the F1 and V antigens of Yersinia pestis at a dose level of 1 μg or 5 μg or with the respective protein sub-units as a reference vaccine.
Robin John Shattock, Voahangy Andrianaivoarimanana, Paul F. McKay, Lovasoa Nomena Randriantseheno, Valarmathy Murugaiah, K. Samnuan, Paul Rogers, John S. Tregoning, Minoarisoa Rajerison, Kristoffer M. Moore, Thomas Robert Laws, E. Diane Williamson   +11 more
doaj   +1 more source

The role of louse-transmitted diseases in historical plague pandemics

The Lancet Infectious Diseases, 2021
The rodent-murine ectoparasite-human model of plague transmission does not correspond with historical details around plague pandemics in Europe. New analysis of ancient genomes reveal that Yersinia pestis was unable to be transmitted by rat fleas until around 4000 Before Present, which challenges the rodent-murine ectoparasite-human model of plague ...
Rémi Barbieri, Rémi Barbieri, Didier Raoult, Michel Drancourt   +3 more
openaire   +4 more sources