Results 81 to 90 of about 9,260,529 (325)

Mapping Plague Risk Using Super Species Distribution Models and Forecasts for Rodents in the Zhambyl Region, Kazakhstan

GeoHealth, 2023
One of the most extensive natural plague centers, or foci, is located in Central Asia, in particular, the Zhambyl region in Southern Kazakhstan. Here, we conducted plague surveillance from 2000 to 2020 in the Zhambyl region in Kazakhstan and confirmed 3 ...
N. M. Rametov, M. Steiner, N. A. Bizhanova, Z. Zh. Abdel, D. T. Yessimseit, B. Z. Abdeliyev, R. S. Mussagalieva   +6 more
doaj   +1 more source

Sympathetic Activation Promotes Kidney Fibrosis in Mice via Macrophage‐Derived N2ICD‐Enriched Extracellular Vesicles

Advanced Science, EarlyView.
Norepinephrine/α2B‐adrenoceptor axis promotes the secretion of Notch2 intracellular domain (N2ICD)‐enriched extracellular vesicles (EVs) from macrophages. These EVs deliver N2ICD into fibroblasts, thereby inducing their activation. Deletion of Notch2 or α2B‐AR in macrophages disrupts N2ICD‐enriched EV formation and alleviates kidney fibrosis in mice ...
Huiwen Ren, Yayan Hou, Chengsen Mu, Yinghong Zheng, Yuanyang Wang, Shumin Guo, Lu Wang, Wenlong Shang, Zhuming Yin, Cheng Dong, Yongsheng Chang, Bin Zhou, Renjie Chai, Ying Yu, Yujun Shen   +14 more
wiley   +1 more source

Actual Aspects of Epidemiological Well-Being Support Anti-PLAgue for Population in Altai Republic

Эпидемиология и вакцинопрофилактика, 2016
Relevance. Despite significant advances in modern medicine in the treatment of infectious diseases, the plague has not lost its relevance and is one of the socially significant epidemic threats as a particularly dangerous infection. Every year, there are
S. V. Balakhonov, V. M. Korzun, S. A. Kosilko, E. P. Mikhailov, L. V. Shchuchinov, A. I. Mishchenko, I. V. Zarubin, E. N. Rozhdestvensky, A. V. Denisov   +8 more
doaj   +1 more source

Estimating the basic reproduction number for the 2015 bubonic plague outbreak in Nyimba district of Eastern Zambia.

PLoS Neglected Tropical Diseases, 2020
BackgroundPlague is a re-emerging flea-borne infectious disease of global importance and in recent years, Zambia has periodically experienced increased incidence of outbreaks of this disease.
Joseph Sichone, Martin C Simuunza, Bernard M Hang'ombe, Mervis Kikonko   +3 more
doaj   +1 more source

Alzheimer’s disease: addressing a twenty-first century plague

RENDICONTI LINCEI, 2015
Alzheimer’s disease represents one of the greatest challenges to the social fabric and health care systems of the world since the great plagues of the Middle Ages.
C. Dobson
semanticscholar   +1 more source

Gene Editing of a Susceptibility LncRNA Enhances Broad‐Spectrum Disease Resistance in Rice without Developmental Trade‐Offs

Advanced Science, EarlyView.
Editing susceptibility lncRNAs offers a strategy to enhance disease resistance without yield loss. RESIS, a domestication‐acquired, pathogen‐induced lncRNA, promotes protein N‐terminal acetylation through its interaction with NatA complex. Knockout of RESIS increases translation and confers broad‐spectrum resistance to both fungal and bacterial ...
Wen‐long Zhao, Ye Cheng, Jia‐hui Huang, Jun‐jie Feng, Hui‐yin Pang, Yi‐chao Qin, Zheng‐tong Chen, Yu Cheng, Jian‐ping Lian, Yan‐fei Zhou, Rui‐rui He, Meng‐qi Lei, Zi‐qin Cao, Lu Yang, Chao Yuan, Jie Jiang, Yue‐qin Chen, Yu‐chan Zhang   +17 more
wiley   +1 more source

D3.2 GRAPEVINE Plagues and Diseases Models v2

, 2023
This document is issued within the frame and for the purpose of the GRAPEVINE project. This project has received funding from the European Union's Innovation and Networks Executive Agency – Connecting Europe Facility (CEF) under Grant AGREEMENT No INEA/CEF/ICT/A2018/1837816; Action No 2018-EU-IA-0091.
Moshou, Dimitrios, Paraskevas, Charalampos, Kechagias, Konstantinos, Pantazi, Xanthoula-Eirini, Tamouridou, Afroditi-Alexandra, Stavridou, Domna, Pliatsidis, Konstantnos, Pantazi, Evdoxi-Glykeria, Fragos, Vasilios, Balduque, Joaquín, Vourlioti, Paraskevi, Kotsopoulos, Stelios, Lacueva-Pérez, Francisco José   +12 more
openaire   +1 more source

Post‐Translational Modifications of TOE3 Regulate Antiviral Defense in Tobacco

Advanced Science, EarlyView.
CK2αL phosphorylates TOE3 and enhances its stability, while FBXL1 promotes the ubiquitination‐degradation of TOE3 via the 26S proteasome. Compared to CK2αL‐phosphorylated TOE3, nonphosphorylated TOE3 shows a much higher affinity for FBXL1 and is more susceptible to ubiquitination‐degradation, thus facilitating viral infection. The regulatory mechanisms
Bolei Jiao, Baijun Wu, Honghui Lin, Dehui Xi   +3 more
wiley   +1 more source

An Overview of the Plague Situation and Its Vectors in Iran [PDF]

Journal of Mazandaran University of Medical Sciences
Plague is an important and serious zoonotic disease caused by the bacterium Yersinia pestis. This study is a narrative review. The required data for the research were gathered through a search in search engines such as Google Scholar and international ...
Seyed Hassan Nikookar, Golnesa Bagheri, Omid Dehghan, Farzaneh Sahraee, Mahmoud Fazeli Dinan, Seyed Farzad Motevalli Haghi, Nasibeh Hosseini-Vasoukolaei, Mohammad Reza Bagheri   +7 more
doaj  

Eighteenth century Yersinia pestis genomes reveal the long-term persistence of an historical plague focus

eLife, 2016
The 14th–18th century pandemic of Yersinia pestis caused devastating disease outbreaks in Europe for almost 400 years. The reasons for plague’s persistence and abrupt disappearance in Europe are poorly understood, but could have been due to either the ...
Kirsten I Bos, Alexander Herbig, Jason Sahl, Nicholas Waglechner, Mathieu Fourment, Stephen A Forrest, Jennifer Klunk, Verena J Schuenemann, Debi Poinar, Melanie Kuch, G Brian Golding, Olivier Dutour, Paul Keim, David M Wagner, Edward C Holmes, Johannes Krause, Hendrik N Poinar   +16 more
doaj   +1 more source