Results 221 to 230 of about 3,310,049 (341)

Treatment with vutrisiran in people with transthyretin amyloidosis with cardiomyopathy: a plain language summary. [PDF]

open access: yesFuture Cardiol
Fontana M   +8 more
europepmc   +1 more source

Amide‐Linked Local Anesthetics Alter Tumor Biology in a Complex Human Tissue Model of Non‐Small Cell Lung Adenocarcinoma

open access: yesAdvanced Biology, EarlyView.
Amide local anesthetics (LA) affect tumor burden in various preclinical studies, possibly via their anti‐inflammatory properties. However, a translation into clinical evidence is still lacking. The current study demonstrates that LA ‐ even at clinically relevant concentrations – exert a strong anti‐tumoral effect in a complex ex vivo model patient ...
Juliane Krömer   +8 more
wiley   +1 more source

Investigation of Iron‐Aluminide‐Like Phase Composition in Complex Concentrated Fe32Cu12Ni11Ti16Al29 Alloy

open access: yesAdvanced Engineering Materials, EarlyView.
This work reveals the phase composition and quantitative morphology analysis of precipitation‐hardened Fe32Cu12Ni11Ti16Al29 complex‐concentrated alloy. The precipitates are shown to have a high coherency. Morphology transition between sphere, cuboidal, and elongated morphology is observed. Finally, the overaging behavior is captured using microhardness.
Rostyslav Nizinkovskyi   +4 more
wiley   +1 more source

Impact of Hot Isostatic Pressing on Microstructure Evolution and Creep Performance of Powder Bed Fusion–Laser Beam Processed CM247LC

open access: yesAdvanced Engineering Materials, EarlyView.
The influence of Hot Isostatic Pressing (HIP) temperature on the microstructure and creep performance of powder bed fusion–laser beam processed CM247LC superalloy is investigated. Grain growth and γ’ precipitate evolution are characterized following HIP at varying temperatures.
Ahmed Fardan   +4 more
wiley   +1 more source

The Effect of Thickness, Build Orientation, and Loading Rate on the Tensile and Compressive Properties of Selective Laser Sintering Polyamide 12 Specimens

open access: yesAdvanced Engineering Materials, EarlyView.
This article examines how build orientation, thickness, and loading rate affect the tensile and compressive properties of LS‐manufactured polyamide 12 12 parts. Through over 120 experiments, it reveals strong ductility anisotropy in tension, minimal compressive sensitivity, and significant thickness and strain rate dependencies.
Andreas Psarros   +2 more
wiley   +1 more source

Effect of Annealing Temperature on Microstructure and Dry‐Sliding Behavior of Powder Bed Fusion–Laser Beam Ti6Al2Sn4Zr6Mo Alloy

open access: yesAdvanced Engineering Materials, EarlyView.
Heat treatment parameters critically affect the wear resistance of powder bed fusion–laser beam (PBF‐LB)‐produced Ti–6Al–2Sn–4Zr–6Mo alloy. This study found that optimizing annealing temperature allows to obtain a tailored microstructure, which enhances the dry‐sliding behavior by forming a stable and functional mechanically mixed layer (MML), ensuring
Gianluca Pirro   +5 more
wiley   +1 more source

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