Results 121 to 130 of about 70,641 (277)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

The NPFIT strategy for information security of care record service [PDF]

, 2011
The National Programme for IT in England doesn’t have a one-document strategy for its information security of the Care Records Service, which is the national EHR system.
Mohammad, Y, Stergioulas, L
core  

Perceived Factors Affecting the Implementation of Occupational Health and Safety Management Systems in the South African Construction Industry

Safety
Although notable efforts have been made in the past to improve Occupational Health and Safety (OHS), the overall performance has not significantly improved as high-level injuries, risks, and fatalities continue to occur.
Rejoice Kunodzia, Luviwe Steve Bikitsha, Rainer Haldenwang   +2 more
doaj   +1 more source

The PDCA(Plan-Do-Check-Act) Cycle’s Roles in Food Quality Improvement

Frontiers in Business, Economics and Management
The rising occurrence of food quality incidents in China has greatly diminished consumer trust and endangered market stability, highlighting the urgent requirement for enhanced quality management systems in food firms. This article examines the use of the PDCA(Plan-Do-Check-Act) cycle as a strategic framework to improve food quality management at ...
openaire   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Luther Midelfort Mayo Health System: Laying Tracks for Success [PDF]

, 2008
Describes strategies for establishing a culture of experimentation, including creating interdisciplinary teams to decide the content of care and providing timely measurement and ...
Jennifer N. Edwards
core  

APPLYING PDCA MODEL IN MANAGING MATHEMATICS TEACHING ACTIVITIES IN PRIMARY SCHOOLS TOWARDS DEVELOPING STUDENTS' CAPACITY - SOME THEORETICAL ISSUES

Tạp chí Khoa học
The PDCA (Plan - Do - Check - Act) model is widely applied in quality management and can be adapted to suit educational settings, particularly in improving teaching quality and fostering student competencies. This article analyzes several theoretical
Do Thi Ha*, Nguyen Thi Huong
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

A Hospital Infection Management Department-Led Intervention to Improve the Pathogen Submission Rate Before Antimicrobial Therapy Using a FOCUS-PDCA Model

Infection and Drug Resistance
Lizhen Xu, Qiufang Tang, Yuxiang Guo, Dan Liu Department of Hospital Infection Management, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, Zhejiang, People’s Republic of ChinaCorrespondence: Lizhen Xu, Department of Hospital ...
Xu L, Tang Q, Guo Y, Liu D
doaj  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source