Results 41 to 50 of about 12,774 (254)
This work is focused on effectiveness of adopting the Plan, Do, Check, Act (PDCA) cycle model, also known as Deming cycle, for an analytical laboratory management.
La Verde Giuseppe +2 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Enhancing the timeliness of EMR documentation in resident doctors: the role of PDCA cycle management
Background The impact of the Plan-Do-Check-Act (PDCA) cycle in improving the timeliness of electronic medical record documentation (EMRd) remains uncertain.
Jiaoting Chen +7 more
doaj +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
The reactivation of the hepatitis B virus (HBV) following systemic chemotherapy reportedly caused acute liver dysfunction as a fatal complication. HBV reactivation sometimes occurs even after the cessation of chemotherapy, especially in the patients with hematological malignancies.
Satoshi Hibi +8 more
openaire +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The intention of this paper is to share some of our experiences with implementing a simple ‘Plan Do Check Act’ (PDCA) cycle within our Learning and Innovation Centre (LIC). The PDCA-cycle is a never ending cycle designed to improve quality and efficiency.
Ellen Simons
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Facility Management using digital Obeya Room by integrating BIM-Lean approaches – an empirical study
This paper applies a methodology for interdisciplinary Facilities Management (FM) by alingment between Building Information Modeling (BIM) and Lean. Initially, the literature review of BIM, FM and Lean principles.
Daniel Luiz de Mattos Nascimento +5 more
doaj +1 more source
Implementation of ISO 9001:2015 in e-Learning services in higher education
Needs for using a Learning Management System (LMS) in curriculum development in higher education is increasing, including what has happened at the Bandung Institute of Technology.
Mochamad Rizal Fikri Gunadi
doaj +1 more source

