Results 41 to 50 of about 494,040 (274)
Proceedings, 2020 The purpose of this paper is to establish the specifications of an analysis and evaluation model in the form of a reference framework for the design, development, implementation, periodic evaluation, and continuous improvement of quality management ...
Flaviu Moldovan
doaj +1 more source
Water Policy, 2022 Improving the governance effectiveness of river basin units (RBUs) is often the focus of academic studies. However, the literature on measuring the influencing factors of the river basin governance effectiveness in urban areas is relatively scarce ...
Chang-Yen Lee, Wen-Jung Chang
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Application of the Plan–Do–Check–Act Cycle in Shortening the Decision to Delivery Interval Time
Risk Management and Healthcare Policy, 2022 Ming-Na Lu, Bai-Lei Zhang, Qiao-Hong Dai, Xian-Hu Fu Department of Obstetrics and Gynecology, Ningbo Women and Children’s Hospital, Ningbo, 315012, People’s Republic of ChinaCorrespondence: Qiao-Hong Dai, Department of Obstetrics and Gynecology, Ningbo ...
Lu MN, Zhang BL, Dai QH, Fu XH
doaj
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
End-of-Life Heart Failure Education With Staff Nurses; A Quality Improvement Project [PDF]
, 2016 Presented to the Faculty of the University of Alaska Anchorage in Partial Fulfillment of the Requirements for the Degree of MASTER OF SCIENCEHeart failure (HF) is a serious diagnosis and a major public health concern.
Battah, Carisa
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Peningkatan dan Perbaikan dari Temuan Audit External ISO 9001 di LP3I College
Majalah Ilmiah Bijak, 2019 The findings of external audits in order to ensure the implementation of ISO 9001 quality management system at LP3I College for three consecutive years provide benefits in the form of improvement, correction and consistency of the quality management ...
Wiwiet Prihatmadji
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source