Results 11 to 20 of about 1,166,890 (164)

Repurposing FDA Drug Compounds against Breast Cancer by Targeting EGFR/HER2

open access: yesPharmaceuticals, 2021
Repurposing studies have identified several FDA-approved compounds as potential inhibitors of the intracellular domain of epidermal growth factor receptor 1 (EGFR) and human epidermal receptor 2 (HER2).
Irving Balbuena-Rebolledo   +3 more
doaj   +1 more source

PLANEACION E INNOVACION

open access: yesCuadernos Latinoamericanos de Administración, 2016
Editorial
Rafael Sánchez París
doaj   +1 more source

Effect of New Analogs of Hexyloxy Phenyl Imidazoline on Quorum Sensing in Chromobacterium violaceum and In Silico Analysis of Ligand-Receptor Interactions

open access: yesJournal of Chemistry, 2020
The increasing common occurrence of antibiotic-resistant bacteria has become an urgent public health issue. There are currently some infections without any effective treatment, which require new therapeutic strategies.
José Luis Herrera-Arizmendi   +4 more
doaj   +1 more source

A Dual Monitoring Technique to Detect Power Quality Transients Based on the Fourth-Order Spectrogram

open access: yesEnergies, 2018
This paper presents a higher-order statistics-based approach of detecting transients that uses the fourth-order discrete spectrogram to monitor the power supply in a node of the domestic smart grid.
Juan-José González-de-la-Rosa   +4 more
doaj   +1 more source

El Plan de Desarrollo Municipal de Bucaramanga 2020-2023 bajo la sombrilla de las nuevas fuerzas del desarrollo

open access: yesInterconectando Saberes, 2021
El presente estudio analiza el Plan de Desarrollo Municipal (PDM) de Bucaramanga para la gestión 2020-2023, en el marco de la teoría de las nuevas fuerzas de desarrollo propuesta por Vázquez (2005): organización flexible de la producción (OFP), difusión ...
Daniel Corzo Arévalo
doaj   +1 more source

Universal functions with prescribed zeros and interpolation properties [PDF]

open access: yes, 2009
Plan Andaluz de Investigación (Junta de Andalucía)Ministerio de Educación y CienciaFondo Europeo de Desarrollo ...
Bernal González, Luis   +2 more
core   +1 more source

Almost 50 Years of Monomeric Extracellular Ubiquitin (eUb)

open access: yesPharmaceuticals
Monomeric ubiquitin (Ub) is a 76-amino-acid highly conserved protein found in eukaryotes. The biological activity of Ub first described in the 1970s was extracellular, but it quickly gained relevance due to its intracellular role, i.e., post ...
Ivette Mendoza-Salazar   +9 more
doaj   +1 more source

Plan de desarrollo y comunicación

open access: yesChasqui, 2015
Un Plan Nacional de Desarrollo debe contar con un componente de comunicación. Así lo entendió y asumió el Gobierno del Ecuador al plantear la propuesta con coraje, consecuencia ideológica y autenticidad política.
Alejandro Alfonzo
doaj   +1 more source

Estrategias para potencializar el turismo de naturaleza mediado por el marketing en busca de la conservación de los bosques amazónicos

open access: yesEntorno Geografico, 2022
En la actualidad, la deforestación es un fenómeno que ha incrementado el impacto del cambio climático. Por ello, el objeto de la investigación se enfoca en estrategias para potencializar el turismo de naturaleza mediado por el marketing en la vereda ...
Diana Alí García Capdevilla   +2 more
doaj   +1 more source

Computationally Guided Design, Synthesis, and Evaluation of Novel Non-Hydroxamic Histone Deacetylase Inhibitors, Based on N-Trifluoroacetamide as a Zinc-Binding Group, Against Breast Cancer

open access: yesPharmaceuticals
Background: Histone deacetylases (HDACs) are enzymes that deacetylate histone proteins, impacting the transcriptional repression and activation of cancer-associated genes such as P53 and Ras.
Gerardo Morales-Herrejón   +5 more
doaj   +1 more source

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