Results 231 to 240 of about 65,333,455 (300)

Understanding How Multisectoral Programs and Policies Across Systems Can Be Leveraged to Improve Maternal, Infant, and Child Nutrition in Guinea. [PDF]

Int J Health Plann Manage
Schwendler TR, Sankhon RH, Jensen L, Fofana ML, Daffé M, Camara F, Zoma R, Balde I, Kodish SR.   +8 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Proposition de plan pour un module de formation : Transition juste et équité sociale.

Les cahiers de pédagogies radicales
openaire   +1 more source

Integrating sensory analysis and voltammetry to explore oxidative susceptibility in red wines. [PDF]

Food Chem X
Bueno M, Sáenz-Navajas MP, Peña C, Arias I, Castillo C, Fernández-Zurbano P, De la Fuente-Blanco A, Ferreira C, Escudero A, Ferreira V.   +9 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Iron-Sulfur Cluster Targeting: A Novel Perspective for Treating Alcohol-Related Lipid Metabolic Diseases. [PDF]

J Biochem Mol Toxicol
Xu L, Xu Z, Su C, Zhao Y, Qiang L, Jing X, Sun Y.   +6 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Implementing a Protocol for Incremental Hemodialysis in Incident Patients With Kidney Failure: A Quality Improvement Initiative. [PDF]

Can J Kidney Health Dis
Messina A, Taha A, Sanchez-Allakhverdieva A, Laurier N, Tom A, Tan V, Filteau N, McKinnon J, Blum D, Weber C, Trinh E.   +10 more
europepmc   +1 more source