Results 101 to 110 of about 63,203,487 (249)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Psychological First Aid: The Derivation and Evaluation of a Training Package for Use in Mountain Rescue

open access: yesInternational Journal of First Aid Education
Problem: A lack of training exists in psychological support that is available to mountain rescue team (MRT) members. Psychological first aid (PFA) is an appropriate framework to provide that support.
Anthony Page
doaj   +2 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Building It So They Will Come: Assessing Universities’ Distance Education Faculty Training and Development Programs

open access: yesInternational Journal of E-learning and Distance Education, 2007
The case for the necessity of distance education faculty training and development is well established, but research that addresses what such programs should look like—as well as what are the key opportunities and constraints—is limited.
Tracy Irani, Ricky Telg
doaj  

Plan de estudios, contenidos mínimos. Tecnicatura en Comercialización. Plan 2014

open access: yes, 2014
Universidad de Belgrano. Facultad de Estudios a Distancia y Educación Virtual. Tecnicaturas universitarias de dos años. Tecnicatura en Comercialización.
Universidad de Belgrano. Facultad de Estudios a Distancia y Educación Virtual. Tecnicaturas universitarias de dos años
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Formation : "Les Plans de Gestion des Logiciels de la Recherche". Questions et Réponses sur le Modèle PRESOFT et les Plans de Gestion [PDF]

open access: yes
L’objectif de ce document est de reprendre certaines questions qui ont été posées par les participants aux deux formations « Les logiciels de la recherche et les licences : trois visions sur un objet avec un atelier sur les Plans de gestion de logiciels », 1 et 8 juin 2026, https://ligm.univ-eiffel.fr/~teresa/presoft/2026FormationLogicielsRecherche/ 
openaire   +4 more sources

Plan regional de desarrollo del sector agropecuario de la IV region: Anexos

open access: yes, 1977
Este documento, contiene los anexos del Plan regional de desarrollo del sector agropecuario de la IV region, los cuales abarca la situación actual y perspectiva de la región en relación a los problemas originados por la escasez de agua; los aportes del ...
Momberg, Alfonso   +3 more
core  

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