Results 111 to 120 of about 65,333,455 (300)

Formation : "Les Plans de Gestion des Logiciels de la Recherche". Questions et Réponses sur le Modèle PRESOFT et les Plans de Gestion [PDF]

open access: yes
L’objectif de ce document est de reprendre certaines questions qui ont été posées par les participants aux deux formations « Les logiciels de la recherche et les licences : trois visions sur un objet avec un atelier sur les Plans de gestion de logiciels », 1 et 8 juin 2026, https://ligm.univ-eiffel.fr/~teresa/presoft/2026FormationLogicielsRecherche/ 
openaire   +4 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Plan regional de desarrollo del sector agropecuario de la IV region: Anexos

open access: yes, 1977
Este documento, contiene los anexos del Plan regional de desarrollo del sector agropecuario de la IV region, los cuales abarca la situación actual y perspectiva de la región en relación a los problemas originados por la escasez de agua; los aportes del ...
Momberg, Alfonso   +3 more
core  

Plan de aforos. Red secundaria 2000: Jaén

open access: yes, 2001
Andalucía. Consejería de Obras Públicas y Transportes; Andalucía. Dirección General de Carreteras; Andalucía. Servicio de Explotación y TecnologíaContiene: Mapa red secundaria 2000.
Andalucía. Consejería de Obras Públicas y Transportes   +2 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Développer sa professionnalité grâce à la vidéo 360° : exemple d'un dispositif pour la formation des professeurs documentalistes

open access: yesMédiations & Médiatisations
En France, les INSPÉ (Instituts nationaux supérieurs du professorat et de l’Éducation) forment les étudiants aux métiers du professorat, de l’éducation et de la formation.
Léa Degeuse, Alain Sénécail
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Bien communiquer sur sa thèse, suite.

open access: yesEspacesTemps.net, 2005
Après une brève présentation sur lui-même, Edouard Paulino du Craft (Centre de recherche et d’appui pour la formation et ses technologies, qui travaille à l’ Epfl ) lance le débat : que signifie communiquer sur sa thèse ?
Philippe Heller
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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