Results 241 to 250 of about 65,333,455 (300)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Patient-Specific Vascular Anatomy for Bedside Safety: A Targeted Narrative Review and the VASC-N Framework. [PDF]

open access: yesNurs Rep
Sanchis-Gimeno JA   +6 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Bridging Access Gaps in Radiotherapy: Knowledge-Based Planning in a Resource-Constrained Clinical Setting. [PDF]

open access: yesCureus
Ixquiac Cabrera ME   +8 more
europepmc   +1 more source

The evolutionary origins of streptophyte multicellularity. [PDF]

open access: yesNew Phytol
Darienko T   +10 more
europepmc   +1 more source

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