Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Le plan de formation en tant qu'outil au service de la performance de l'organisation
Ce chapitre traite en particulier de l'intérêt des plans de formation dans le contexte de la formation policière en Belgique.
Demeuse, Marc +2 more
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Nouveau plan de formation pour les assistantes mdicales CFC [PDF]
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Elaborer un plan de recrutement et de formation pour les animateurs périscolaires
Cet article trouve son origine dans la journée d'étude "Aménagement des rythmes scolaires et animation" organisée par le département Carrières Sociales de l'I.U.T. de Nice en mars 2014 à Menton Soucieux des nécessités réglementaires, des besoins de fonctionnement et des difficultés pour recruter des personnels qualifiés, l'article propose une ...
openaire +1 more source
Novel post-transcriptional dimension of glucocorticoid action through mRNA translation and P-body remodeling. [PDF]
Nicolini VJ +2 more
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
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<i>Acanthus mollis</i> Leaf Extract as Potential New Food Ingredient in the Prevention of Aging-Related Neurodegeneration. [PDF]
Cavalloro V +7 more
europepmc +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Bridging Access Gaps in Radiotherapy: Knowledge-Based Planning in a Resource-Constrained Clinical Setting. [PDF]
Ixquiac Cabrera ME +8 more
europepmc +1 more source

