Results 91 to 100 of about 785,168 (303)

Security in northeast Asia: structuring a settlement [PDF]

, 2019
A potential pathway exists for a Northeast Asian settlement where the Koreas, the United States, China, and Japan can each live within the status quo. Sustaining a settlement will require reining in foreign policy hawks reluctant to allow the Democratic
Shifrinson, Joshua
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Programa de prevención secundaria en pacientes con fractura de cadera

Revista del Hospital Italiano de Buenos Aires
Las fracturas de cadera constituyen un problema de Salud Pública mundial. La morbimortalidad asociada a este evento genera “exceso de mortalidad”, dependencia, internación en geriátricos y altos costos en los diferentes sistemas de salud. El tratamiento
Adriana Marta Trossero, Andrea Beratarrechea, María Diehl, Javier Saimovici, Natalia Pace, Fabiana Giber, Eugenia Quintar, Juan Padín, Gimena Giardini, Mariela Murakami, Ileana Donnianni, Gustavo Vidal, Francisco Piccaluga, Carlos Sancineto, Karin Kopitowski, Esteban Langlois, Gastón Perman, Luisa Plantalech   +17 more
doaj  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Nuclear arsenal reduction plan for the United States [PDF]

, 2012
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Nuclear Science and Engineering, 2012."June 2012." Cataloged from PDF version of thesis.Includes bibliographical references (p.
Laderman, Sarah (Sarah Jane)
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Spectroscopy of eta'-nucleus bound states at GSI-SIS

, 2012
The eta' meson mass may be reduced due to partial restoration of chiral symmetry. If this is the case, an eta'-nucleus system may form a nuclear bound state. We plan to carry out a missing-mass spectroscopy with the 12C(p,d) reaction at GSI-SIS.
A. Wrońska, C. Guaraldo, Daisuke Jido, H. Ströher, Hans Geissel, Haruhiko Outa, Helmut Weick, Hideko Nagahiro, Hiroyuki Fujioka, Ken Suzuki, Kenta Itahashi, Kota Okochi, Mariana Nanova, R. Skibiński, Ryugo S. Hayano, Satoru Hirenzaki, Satoshi Itoh, St. Kistryn, Takahiro Nishi, Takatoshi Suzuki, Volker Metag, Yoshiki K. Tanaka   +21 more
core   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Strategic analysis for advancing Morocco's nuclear infrastructure using PESTELE framework

Nuclear Analysis
Morocco's exploration of nuclear energy aligns with both climate goals and national energy ambitions, offering a promising low-carbon alternative to conventional fossil fuels.
Hafsa Housni, Naila Amrous, Najima Daoudi, Mohamed Jaouad Malzi   +3 more
doaj   +1 more source