Results 41 to 50 of about 133,107 (260)
Frontiers in Energy Research, 2022 The significant impact brought by a severe nuclear accident at the Fukushima Daiichi Nuclear Power Plant (NPP) in Japan in March 2011 has made global regulators to review the requirements against severe accidents.
Zhiyi Yang, Fengchen Li, Guohan Chai
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
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EPJ Web of Conferences, 2017 A comprehensive research program on deuteron nuclear data motivated by development of accelerator-based neutron sources is being executed. It is composed of measurements of neutron and gamma-ray yields and production cross sections, modelling of deuteron-
Watanabe Yukinobu +4 more
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
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Conception of digital nuclear power station
Dianxin kexue, 2016 A new digital nuclear power station architecture blueprint and plan were put forward. With the concept of the full lifecycle management of nuclear power station，design data，construction data，commissioning data，real-time data and business process data for
Yingrong WANG, Xiuliang XU, Shuyuan CAO
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Jurnal Ilmu Sosial dan Ilmu PolitikOne form of potential threat faced by Indonesia is an energy crisis that can disrupt national stability. However, the use of nuclear as an alternative source of clean energy through Nuclear Power Plants (PLTN) has not been realized until now.
Syahdino Pratama +3 more
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Energy Crisis and the Need to Enhance Nuclear Energy in Pakistan
NUST Journal of Engineering Sciences, 2010 Energy crisis is the immense shortfall in the supply of energy resources including electricity. Due to increase in the consumption of electricity, Pakistan is facing the worst power crisis of its history.
Faisal Asfand, Muhammad Sadiq
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