Results 81 to 90 of about 371,700 (244)

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Single camera three component planar velocity measurements, using two frequency Planar Doppler Velocimetry (2v-PDV) (2005) [PDF]

, 2005
The work presented here describes a method that allows three component velocity measurements to be made, quickly and non-intrusively, across a plane in a flow defined by a laser light sheet. The method, two frequency planar Doppler Velocimetry (2v-PDV)
Charrett, Thomas O. H., Helen D. Ford, Ralph P. Tatam, Tatam, Ralph P., Tom O. H. Charrett, Ford, Helen D.   +5 more
core   +1 more source

Contactless object manipulation using multiple air jets on planar surface (Experimental case studies for small control range with continuous air jets)

Nihon Kikai Gakkai ronbunshu, 2014
We propose a technology for manipulating the position and attitude of an object on a planar surface in a contactless manner. This technology involves multiple ejectors that stream jets of compressed air onto an object from various directions.
Tsubasa MATSUSHITA, Takatoshi SUGIYAMA, Kazuya TSUJI, Satoshi IWAKI, Kazuhiro TANIGUCHI, Minoru KOBAYASHI, Takeshi TAKAKI, Idaku ISHII, Toshiro NORITSUGU   +8 more
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Planar Turán Numbers of Cycles: A Counterexample [PDF]

, 2022
The planar Turán number exP(Cℓ, n) is the largest number of edges in an n-vertex planar graph with no ℓ-cycle. For each ℓ ∈ {3, 4, 5, 6}, upper bounds on exP(Cℓ, n) are known that hold with equality infinitely often.
Liu, Xiaonan, Lidicky, Bernard, Shantanam, Abhinav, Cranston, Daniel W.   +3 more
core  

Combination Actuator of the Linear Coordinate System of Technological Equipment with Control Propulsive Force

Механика машин, механизмов и материалов, 2013
The problems of constructing of linear drives with traditional toothed belt transmissions for coordinate systems of technological equipment, used for cutting semiconductor wafers with diamond wheel are discussed.
V.L. Basinyuk , E.I. Mardosevich , S.S. Papina , V.G. Lomako   +3 more
doaj  

Dual Circularly Polarized Planar Four-Port MIMO Antenna with Wide Axial-Ratio Bandwidth

Sensors, 2020
A broadband compact-sized planar four-port multiple-input–multiple-output (MIMO) antenna with polarization diversity is presented. The proposed dual circularly polarized (CP) MIMO antenna consists of four G-shaped monopole elements, two of which are left-
Sachin Kumar, Gwan Hui Lee, Dong Hwi Kim, Hyun Chul Choi, Kang Wook Kim   +4 more
doaj   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Under-Coupling Whispering Gallery Mode Resonator Applied to Resonant Micro-Optic Gyroscope

Sensors, 2017
As an important sensing element, the whispering gallery mode resonator (WGMR) parameters seriously affect the resonant micro-optic gyroscope (RMOG) performance.
Kun Qian, Jun Tang, Hao Guo, Wenyao Liu, Jun Liu, Chenyang Xue, Yongqiu Zheng, Chengfei Zhang   +7 more
doaj   +1 more source