Results 51 to 60 of about 38,874 (304)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Planar sensors for dosimetry in mixed gamma-neutron fields [PDF]

Ядерна фізика та енергетика, 2007
Circular silicon p-i-n diodes fabricated by planar technology have been studied. The diodes allow simultaneously measurements of neutron doses and gamma dose rates in mixed fields.
I. E. Anokhin, O. S. Zinets, A. B. Rosenfeld, M. Yudelev, V. L. Perevertailo   +4 more
doaj  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Optimal design of bi-planar heater with magnetic field self-suppression configuration based on multi-objective optimization

Results in Physics, 2023
As a crucial component, the vapor cell serves as the fundamental sensing element in various atomic sensors, and electric heating is typically required to enhance the density of alkali metal atoms.
Huimin Wang, Shuying Wang, Bo Li, Yujie Qian, Jixi Lu   +4 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Improved sensing characteristics of dual-gate transistor sensor using silicon nanowire arrays defined by nanoimprint lithography

Science and Technology of Advanced Materials, 2017
This work describes the construction of a sensitive, stable, and label-free sensor based on a dual-gate field-effect transistor (DG FET), in which uniformly distributed and size-controlled silicon nanowire (SiNW) arrays by nanoimprint lithography act as ...
Cheol-Min Lim, In-Kyu Lee, Ki Joong Lee, Young Kyoung Oh, Yong-Beom Shin, Won-Ju Cho   +5 more
doaj   +1 more source

Advances and key technologies in magnetoresistive sensors with high thermal stabilities and low field detectivities

APL Materials, 2022
Advances in micro- and nanotechnology have led to rapid employment of spintronic sensors in both recording and non-recording applications. These state-of-the-art magnetoresistive spintronic sensors exhibit high sensitivities and ultra-low field ...
Byeonghwa Lim, Mohamed Mahfoud, Proloy T. Das, Taehyeong Jeon, Changyeop Jeon, Mijin Kim, Trung-Kien Nguyen, Quang-Hung Tran, Ferial Terki, CheolGi Kim   +9 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Micro and Nano Interdigitated Electrode Array (IDEA)-Based MEMS/NEMS as Electrochemical Transducers: A Review

Nanomaterials, 2022
Micro and nano interdigitated electrode array (µ/n-IDEA) configurations are prominent working electrodes in the fabrication of electrochemical sensors/biosensors, as their design benefits sensor achievement.
Elyana Kosri, Fatimah Ibrahim, Aung Thiha, Marc Madou   +3 more
doaj   +1 more source

Planar Microwave Sensors: State of the Art and Applications

IEEE Access
CARLOS G Juan, Katia Grenier, Mohammad H Zarifi   +2 more
exaly   +2 more sources