Results 91 to 100 of about 3,802,470 (275)

Firms'productive performance and the investment climate in developing economies : an application to MENA manufacturing [PDF]

open access: yes
Drawing on the World Bank Investment Climate Assessment surveys, this paper investigates the relationship between firm-level technical efficiency and the investment climate for 22 developing economies and eight manufacturing industries. The authors first
Kinda, Tidiane   +2 more
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Capital Flows and their Impact on the Real Effective Exchange Rate [PDF]

open access: yes
This paper analyzes the impact of capital inflows and the exchange rate regime on the real effective exchange rate. A wide range of developing countries (42 countries) is considered with estimation based on panel cointegration techniques.
Jean-Louis Combes   +2 more
core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Unsteady flow of droplet liquid in hydraulic systems of aircrafts and helicopters: models and analytical solutions

open access: yesАвіаційно-космічна техніка та технологія
The subject of this study is the unsteady flow of liquid in pipelines, which are part of the design of airplanes and helicopters. This name means, first of all, the phenomenon of a sharp increase in pressure in the pipeline, which is known as a hydraulic
Pavlo Lukianov, Kateryna Pavlova
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Os produtores às voltas com o tempo e com a memória

open access: yesLinha D'Água, 2016
Este artigo aborda as relações entre a escrita o tempo e a memória. Examina em primeiro lugar a maneira como a escrita se inscreve na temporalidade complexa e evoca as consequências que esse fato tem sobre a atividade de linguagem do produtor de texto ...
Sylvie Plane, Ana Lucia Tinoco Cabral
doaj   +1 more source

Observation of two species of vortices in the anisotropic spin-triplet superconductor $Sr_2 Ru O_4$

open access: yes, 2006
Magnetic flux structures in single crystals of the layered spin triplet superconductor Sr$\_{2}$RuO$\_{4}$ are studied by scanning micro SQUID Force microscopy.
A. I. Buzdin   +5 more
core   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

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