Results 231 to 240 of about 3,802,470 (275)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Design and validation of a high-speed rotor balancer based on influence coefficient method and dual-speed control. [PDF]

Sci Rep
Gharehcheloo PK, Saberi FF, Shamshirsaz M.   +2 more
europepmc   +1 more source

Natural hyperbolicity of hexagonal boron nitride in the deep ultraviolet. [PDF]

Nat Commun
Choi B, Lynch J, Chen W, Jeon SJ, Cho H, Yang K, Kim J, Engheta N, Jariwala D.   +8 more
europepmc   +1 more source

In Situ Imaging Reveals Efficient Charge Separation in Monolayer MoS₂-WS₂ Type-II Heterojunctions. [PDF]

J Am Chem Soc
Huang Q, Wang Z, Liu R, Yao H, Ni C, Bo T, Wu S, Sun F, Fan F, Mirkin MV.   +9 more
europepmc   +1 more source

Determination of Fracture Mechanism and Mode II Fracture Toughness of Red Sandstone Subjected to Compressive-Shear Loading. [PDF]

Materials (Basel)
Lei CH, Liu HZ, Xie HQ, Xiao ML, Feng G, Zheng ZQ.   +5 more
europepmc   +1 more source

Apparent diffusion coefficient of kidneys with non-contrast magnetic resonance angiography for functional and anatomical assessment in renal artery stenosis. [PDF]

World J Methodol
Lal H, Agarwal S, Ponmalai K, Prasad R, Bhadauria DS, Gambhir S, Mandal S, Kumar S, Yadav P, Jowel P.   +9 more
europepmc   +1 more source

Light-induced bimerons in a chiral magnet. [PDF]

Nat Commun
Zhu K, Rybakov FN, Wang Z, Gao W, Sun S, Wang W, Li J, Tian H, Eriksson O, Yang H, Zhang Y, Kiselev NS, Li Z, Li J.   +13 more
europepmc   +1 more source