Results 41 to 50 of about 2,442,403 (293)
Solving olympiad geometry without human demonstrations
NatureProving mathematical theorems at the olympiad level represents a notable milestone in human-level automated reasoning1–4, owing to their reputed difficulty among the world’s best talents in pre-university mathematics. Current machine-learning approaches,
Trieu H. Trinh +4 more
semanticscholar +1 more source
FEBS Letters, EarlyView.PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley +1 more source
Form-Finding of Funicular Geometries in Spatial Arch Bridges through Simplified Force Density Method
Applied Sciences, 2018 In a “classical„ vertical planar arch bridge subjected only to in-plane loads, its funicular geometry (which is the geometry that results in an equilibrium state free from bending stresses, i.e., simply under axial forces) is contained within
Juan José Jorquera-Lucerga
doaj +1 more source
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Direct Laser Writing of Graphene Nanoribbon Thin Films for Supercapacitor Electrodes
Electrochemistry, 2020 Recent developments of low-power electronic devices have triggered interests towards small-scale energy storage. One promising approach is to fabricate micro-supercapaciors (MSCs).
Masahiro SHINKAWA +3 more
doaj +1 more source
A Novel Calibration Method of Line Structured Light Plane Using Spatial Geometry
Sensors, 2023 The line structured light plane calibration method using a plane target cannot produce satisfactory calibration results due to inaccurate positioning of the calibrated points. Field of view noise and sensor noise affect the target light stripe extraction
Huiping Gao, Guili Xu, Zhongchen Ma
doaj +1 more source
Electrostatic patch effects in Casimir-force experiments performed in the sphere-plane geometry [PDF]
, 2012 Patch potentials arising from the polycrystalline structure of material samples may contribute significantly to measured signals in Casimir force experiments.
R. Behunin +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Geometric Curvatures of Plane Symmetry Black Hole
Advances in High Energy Physics, 2013 We study the properties and thermodynamic stability of the plane symmetry black hole from the viewpoint of geometry. We find that the Weinhold curvature gives the first-order phase transition at N=1, where N is a parameter of the plane symmetry black ...
Shao-Wen Wei +3 more
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source