Results 101 to 110 of about 569,825 (280)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Facial [r,s,t]-Colorings of Plane Graphs

open access: yesDiscussiones Mathematicae Graph Theory, 2019
Let G be a plane graph. Two edges are facially adjacent in G if they are consecutive edges on the boundary walk of a face of G. Given nonnegative integers r, s, and t, a facial [r, s, t]-coloring of a plane graph G = (V,E) is a mapping f : V ∪ E → {1, . .
Czap Július   +3 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

An Extension of Kotzig’s Theorem

open access: yesDiscussiones Mathematicae Graph Theory, 2016
In 1955, Kotzig proved that every 3-connected planar graph has an edge with the degree sum of its end vertices at most 13, which is tight. An edge uv is of type (i, j) if d(u) ≤ i and d(v) ≤ j.
Aksenov Valerii A.   +2 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Odd facial total-coloring of unicyclic plane graphs [PDF]

open access: yesDiscrete Mathematics Letters, 2022
Július Czap
doaj   +1 more source

Galois connections between sets of paths and closure operators in simple graphs

open access: yesOpen Mathematics, 2018
For every positive integer n,we introduce and discuss an isotone Galois connection between the sets of paths of lengths n in a simple graph and the closure operators on the (vertex set of the) graph.
Šlapal Josef
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Rainbowness of plane graphs

open access: yesElectronic Notes in Discrete Mathematics, 2007
Abstract The rainbowness, rb ( G ) , of a connected plane graph G is the minimum number k such that any colouring of vertices of the graph G using at least k colours involves a face all vertices of which receive distinct colours. We give a survey on recent results concerning ranbowness of plane graphs.
openaire   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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