Results 131 to 140 of about 543,681 (314)

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Unordered Love in infinite directed graphs

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1992
A digraph D=(V,A) has the Unordered Love Property (ULP) if any two different vertices have a unique common outneighbor. If both (V,A) and (V,A−1) have the ULP, we say that D has the SDULP.
Peter D. Johnson
doaj   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Models of Klein Surface Obstruction Graphs

open access: yesКібернетика та комп'ютерні технології
The task of researching the structure of graphs of given connectivity, which are obstructions for a given surface of non-oriented kind, and building their models, from which obstruction graphs are formed by removing or compressing a set of edges, is ...
Volodymyr Petrenjuk, Dmytro Petreniuk
doaj   +1 more source

Nilpotent graphs with crosscap at most two

open access: yesAKCE International Journal of Graphs and Combinatorics, 2018
Let be a commutative ring with identity. The nilpotent graph of , denoted by , is a graph with vertex set , and two vertices and are adjacent if and only if is nilpotent, where .
A. Mallika, R. Kala
doaj   +1 more source

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

open access: yesMolecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul   +11 more
wiley   +1 more source

A new 4-chromatic edge critical Koester graph [PDF]

open access: yesDiscrete Mathematics Letters, 2023
Andrey A. Dobrynin
doaj   +1 more source

Visibility Graphs of Point Sets in the Plane [PDF]

open access: yesDiscrete & Computational Geometry, 2006
The visibility graph $\mathcal {V}(X)$ of a discrete point set X⊂ℝ2 has vertex set X and an edge xy for every two points x,y∈X whenever there is no other point in X on the line segment between x and y. We show that for every graph G, there is a point set X∈ℝ2, such that the subgraph of $\mathcal {V}(X\cup \mathbb {Z}^{2})$ induced by X is isomorphic to 
openaire   +4 more sources

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

open access: yesMolecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy